Transcription Factor

Accessions: ELK4_DBD (HumanTF 1.0)
Names: ELK4, ELK4_HUMAN, ETS domain-containing protein Elk-4, SAP-1, Serum response factor accessory protein 1, SRF accessory protein 1
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: P28324
Notes: Ensembl ID: ENSG00000158711; DNA-binding domain sequence; TF family: ETS; Clone source: Megaman
Length: 111
Pfam Domains: 5-86 Ets-domain
Sequence:
(in bold interface residues)
1 MDSAITLWQFLLQLLQKPQNKHMICWTSNDGQFKLLQAEEVARLWGIRKNKPNMNYDKLS 60
61 RALRYYYVKNIIKKVNGQKFVYKFVSYPEILNMDPMTVGRIEGDCESLNFS
Interface Residues: 57, 58, 60, 61, 62, 63, 64, 65, 66, 67, 70, 79
3D-footprint Homologues: 4uno_A, 3jtg_A, 7jsa_J, 3zp5_A, 2stt_A, 8ee9_F, 4mhg_A, 1dux_F, 4l18_B, 1yo5_C, 1awc_A, 4lg0_B, 4bqa_A, 1bc8_C, 2w42_A, 4iri_A
Binding Motifs: ELK4_DBD aCCGGAAryr
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

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