Transcription Factor

Accessions: JUNB (HT-SELEX2 May2017)
Names: ENSG00000171223, JUNB
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: bZIP experiment: HT-SELEX Hamming distance: 1 cycle: 4, TF family: bZIP experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 4
Length: 107
Pfam Domains: 26-89 bZIP transcription factor
32-86 Basic region leucine zipper
Sequence:
(in bold interface residues)
1 EEPQTVPEARSRDATPPVSPINMEDQERIKVERKRLRNRLAATKCRKRKLERIARLEDKV 60
61 KTLKAENAGLSSTAGLLREQVAQLKQKVMTHVSNGCQLLLGVKGHAF
Interface Residues: 34, 37, 38, 39, 41, 42, 45, 46
3D-footprint Homologues: 7x5e_F, 2wt7_A, 4eot_A, 7x5e_E, 1gd2_G, 2dgc_A, 5vpe_C, 5vpe_D, 5t01_B
Binding Motifs: JUNB_2 gATGACGTCAyc
JUNB_methyl_1 sATGAsTCAys
Related annotations: PaperBLAST

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