Transcription Factor

Accessions: 3w6v_A (3D-footprint 20231221)
Names: AdpA, AraC family transcriptional regulator, Q9S166_STRGR
Organisms: Streptomyces griseus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q9S166
Length: 111
Pfam Domains: 13-51 Bacterial regulatory helix-turn-helix proteins, AraC family
24-102 Helix-turn-helix domain
63-101 Bacterial regulatory helix-turn-helix proteins, AraC family
Sequence:
(in bold interface residues)
1 SDPLAEVVAWALEHLHEQFDVETLAARAYMSRRTFDRRFRSLTGSAPLQWLITQRVLQAQ 60
61 RLLETSDYSVDEVAGRCGFRSPVALRGHFRRQLGSSPAAYRAAYRARRPQG
Interface Residues: 31, 32, 33, 34, 36, 37, 40, 58, 59, 61, 62, 81, 82, 83, 84, 86, 87, 91, 98, 109
3D-footprint Homologues: 6ml4_A, 7vwz_G, 3w6v_A, 1xs9_A, 3jso_B, 1zgw_A, 6e94_A
Binding Motifs: 3w6v_A cCGcCA
Binding Sites: 3w6v_B
3w6v_C
Publications: Yao M.D, Ohtsuka J, Nagata K, Miyazono K, Zhi Y, Ohnishi Y, Tanokura M. Complex structure of the DNA-binding domain of AdpA, the global transcription factor in Streptomyces griseus, and a target duplex DNA reveals the structural basis of its tolerant DNA sequence specificity. The Journal of biological chemistry 288:31019-29 (2013). [Pubmed]
Related annotations: PaperBLAST

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