Transcription Factor

Accessions: UP00010A (UniPROBE 20160601)
Names: Activating enhancer-binding protein 2 beta, AI606113, AP-2(beta), AP2-beta, E130018K07Rik, Tcfap2b, Tfap2b, transcription factor AP-2 beta
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q61313
Description: transcription factor AP-2 beta
Length: 238
Pfam Domains: 18-221 Transcription factor AP-2
Sequence:
(in bold interface residues)
1 LMMNKDGFLGGMSVNTGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGG 60
61 VLRRAKSKNGGRSLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYICETE 120
121 FPAKAVSEYLNRQHTDPSDLHSRKNMLLATKQLCKEFTDLLAQDRTPIGNSRPSPILEPG 180
181 IQSCLTHFSLITHGFGAPAICAALTALQNYLTEALKGMDKMFLNNTTNRHTSGEGPGS
Interface Residues: 31, 65, 66
3D-footprint Homologues: 8j0k_B
Binding Motifs: UP00010A_1 tyGCCybarGGCaw
UP00010A_2 dkwGCCksmGGCrht
Binding Sites: CCCCAGGC
CCCCAGGG
CCCCCGGG
CCCCGAGG
CCCCGGGG
CCCGAGGC
CCCGAGGG
CCCTAGGC
CCCTAGGG
CCCTCAGG
CCCTTAGG
CCGCAGGC
CCGGGGGC
CCTAAGGC
CCTAGGGC
CCTCAGGC
CCTCCGGC
CCTCGGGC
CCTGAGGC
CCTGGGGC
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

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