Transcription Factor
| Accessions: | UP00010A (UniPROBE 20160601) |
| Names: | Activating enhancer-binding protein 2 beta, AI606113, AP-2(beta), AP2-beta, E130018K07Rik, Tcfap2b, Tfap2b, transcription factor AP-2 beta |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q61313 |
| Description: | transcription factor AP-2 beta |
| Length: | 238 |
| Pfam Domains: | 18-221 Transcription factor AP-2 |
| Sequence: (in bold interface residues) | 1 LMMNKDGFLGGMSVNTGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGG 60 61 VLRRAKSKNGGRSLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYICETE 120 121 FPAKAVSEYLNRQHTDPSDLHSRKNMLLATKQLCKEFTDLLAQDRTPIGNSRPSPILEPG 180 181 IQSCLTHFSLITHGFGAPAICAALTALQNYLTEALKGMDKMFLNNTTNRHTSGEGPGS |
| Interface Residues: | 31, 65, 66 |
| 3D-footprint Homologues: | 8j0k_B |
| Binding Motifs: | UP00010A_1 tyGCCybarGGCaw UP00010A_2 dkwGCCksmGGCrht |
| Binding Sites: | CCCCAGGC CCCCAGGG CCCCCGGG CCCCGAGG CCCCGGGG CCCGAGGC CCCGAGGG CCCTAGGC CCCTAGGG CCCTCAGG CCCTTAGG CCGCAGGC CCGGGGGC CCTAAGGC CCTAGGGC CCTCAGGC CCTCCGGC CCTCGGGC CCTGAGGC CCTGGGGC |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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