Transcription Factor

Accessions: T076992_1.02 (CISBP 1.02)
Names: efl-2, T076992_1.02;
Organisms: Caenorhabditis elegans
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:E2F
Length: 358
Pfam Domains: 36-99 E2F/DP family winged-helix DNA-binding domain
55-93 Sugar-specific transcriptional regulator TrmB
Sequence:
(in bold interface residues)
1 MDPSSIDLGSIPGGSEQQQHEDGAAAAAGSPKEVFRSQQSLGLITQRFMSLRQRNEVLNL 60
61 NEVAKELNISKRRVYDVINVLEGLGYVEKVEKNNIRWIGDNNNSEEQNALEARVEMLRQQ 120
121 EKLLELMIRDAQAIIELHFEDPIERPYNYVSKEDIRKTAEPNTKSIIVKSELDTSSSFEI 180
181 QVTDPSTSGSHDMIVRNKNGVKSHALLFTNDPPEYGDEEDEDDVKKLSSQKRFETSEALR 240
241 VTLAEMLTDPTTISSSPKHIKLEEPEEIDTEDLETFVLPPSTSASQSNAPYLPETPGRGL 300
301 FFSPFKSLIDPCILPSFSDDLTSGYINITTPSRATGAGAGASGQEDEEPVSVMDFFSD
Interface Residues: 45, 52, 298
3D-footprint Homologues: 7o0h_A, 7o0g_A, 8urq_A
Binding Motifs: M0674_1.02 wksGCGsgyw
Related annotations: PaperBLAST

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