Transcription Factor

Accessions: T083773_1.02 (CISBP 1.02)
Names: Q91765, T083773_1.02;
Organisms: Xenopus laevis, Xenopus sp.
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: family:Forkhead
Length: 434
Pfam Domains: 17-148 Forkhead N-terminal region
149-244 Fork head domain
348-423 HNF3 C-terminal domain
Sequence:
(in bold interface residues)
1 MLGAVKMEGHEATDWSSYYGEAEAYSSVGNMNAGLSMNPMNTYMSMSAMRTSANMTASSM 60
61 NMSYVNTGMSPSLTGMSPGTGAMTGMGTGVPSMASHLSPSMIPMSAQTTAMNALAPYTNI 120
121 NSMSPIYGQSNINRSRDPKTYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIM 180
181 DLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLR 240
241 RQKRFKCEKKPSLREGGGKKLSEGASSVGSAANSSSESSVGNESPHSSSSPCQEQKRSLV 300
301 DMKSSQGLSPKHATSPASQAQHLLSQHHSVLSHEAQSHLKPEHHYSFNHPFSINNLMSSE 360
361 QQHHHHHHHNHHHHHKMDLKAYEQVMHYSSYGSPMAGSLAMSTVTNKSGLESSPITSDTS 420
421 YYQGGYSRPIMNSS
Interface Residues: 98, 99, 139, 141, 143, 144, 146, 152, 192, 194, 195, 196, 198, 199, 200, 202, 203, 212, 219, 244
3D-footprint Homologues: 6fn0_A, 7yz7_A, 7yzb_A, 7vox_H, 2hdc_A, 2uzk_A, 7tdx_A, 2a07_J, 6nce_A, 3co6_C, 7vou_C, 6ako_C, 2c6y_A, 7yze_A, 7cby_C, 3g73_A, 6el8_A, 7yzg_A, 7tdw_A, 3l2c_A, 3qrf_G
Binding Motifs: M4105_1.02 wgwGTmAACAwwmw
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.