Transcription Factor
| Accessions: | P10243 (JASPAR 2024) |
| Names: | A-Myb, Myb-like protein 1, Myb-related protein A, MYBA_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P10243 |
| Length: | 752 |
| Pfam Domains: | 35-81 Myb-like DNA-binding domain 38-98 Myb-like DNA-binding domain 87-133 Myb-like DNA-binding domain 90-147 Myb-like DNA-binding domain 139-183 Myb-like DNA-binding domain 142-195 Myb-like DNA-binding domain 239-286 LMSTEN motif 486-649 C-myb, C-terminal |
| Sequence: (in bold interface residues) | 1 MAKRSRSEDEDDDLQYADHDYEVPQQKGLKKLWNRVKWTRDEDDKLKKLVEQHGTDDWTL 60 61 IASHLQNRSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGR 120 121 IGKQCRERWHNHLNPEVKKSSWTEEEDRIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHW 180 181 NSTMRRKVEQEGYLQDGIKSERSSSKLQHKPCAAMDHMQTQNQFYIPVQIPGYQYVSPEG 240 241 NCIEHVQPTSAFIQQPFIDEDPDKEKKIKELEMLLMSAENEVRRKRIPSQPGSFSSWSGS 300 301 FLMDDNMSNTLNSLDEHTSEFYSMDENQPVSAQQNSPTKFLAVEANAVLSSLQTIPEFAE 360 361 TLELIESDPVAWSDVTSFDISDAAASPIKSTPVKLMRIQHNEGAMECQFNVSLVLEGKKN 420 421 TCNGGNSEAVPLTSPNIAKFSTPPAILRKKRKMRVGHSPGSELRDGSLNDGGNMALKHTP 480 481 LKTLPFSPSQFFNTCPGNEQLNIENPSFTSTPICGQKALITTPLHKETTPKDQKENVGFR 540 541 TPTIRRSILGTTPRTPTPFKNALAAQEKKYGPLKIVSQPLAFLEEDIREVLKEETGTDLF 600 601 LKEEDEPAYKSCKQENTASGKKVRKSLVLDNWEKEESGTQLLTEDISDMQSENRFTTSLL 660 661 MIPLLEIHDNRCNLIPEKQDINSTNKTYTLTKKKPNPNTSKVVKLEKNLQSNCEWETVVY 720 721 GKTEDQLIMTEQARRYLSTYTATSSTSRALIL |
| Interface Residues: | 35, 70, 71, 74, 75, 78, 79, 87, 121, 122, 123, 124, 126, 127, 130, 131, 132, 174, 177, 178, 181 |
| 3D-footprint Homologues: | 1w0t_A, 7xur_A, 1vfc_A, 2kdz_A |
| Binding Motifs: | MA0776.1 ACCGTTAACsgy |
| Publications: | Tang H, Goldberg E. A-MYB (MYBL1) stimulates murine testis-specific Ldhc expression via the cAMP-responsive element (CRE) site. Biol Reprod 86:30 (2012). [Pubmed] |
| Related annotations: | PaperBLAST |
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