Transcription Factor

Accessions: T093386_1.02 (CISBP 1.02)
Names: T093386_1.02;, TGIF1
Organisms: Homo sapiens
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: family:Homeodomain
Length: 252
Pfam Domains: 16-72 Homeobox domain
33-72 Homeobox KN domain
Sequence:
(in bold interface residues)
1 MDIPLDLSSSAGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTL 60
61 QVCNWFINARRRLLPDMLRKDGKDPNQFTISRRGAKISETSSVESVMGIKNFMPALEETP 120
121 FHSCTAGPNPTLGRPLSPKPSSPGSVLARPSVICHTTVTALKDVPFSLCQSVGVGQNTDI 180
181 QQIAAKNFTDTSLMYPEDTCKSGPSTNTQSGLFNTPPPTPPDLNQDFSGFQLLVDVALKR 240
241 AAEMELQAKLTA
Interface Residues: 15, 16, 17, 18, 19, 20, 21, 63, 64, 67, 68, 69, 71, 72
3D-footprint Homologues: 4j19_B, 3cmy_A, 6fqp_B, 1zq3_P, 2lkx_A, 1mnm_C, 1puf_B, 1le8_B, 1le8_A, 5zjt_E, 2d5v_B, 1fjl_B, 2hdd_A, 1k61_B, 6fqq_E, 4xrm_B, 1du0_A, 7psx_B, 2hos_A
Binding Motifs: M4064_1.02 AgCTGTCAgdw
Related annotations: PaperBLAST

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