Transcription Factor
| Accessions: | UP00038A (UniPROBE 20160601), UP00406A (UniPROBE 20160601) |
| Names: | Prostate epithelium-specific Ets transcription factor, Prostate-derived Ets factor, Prostate-specific Ets, Pse, SAM pointed domain containing ets transcription factor, SAM pointed domain-containing Ets transcription factor, Spdef |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q9WTP3 |
| Description: | SAM pointed domain containing ets transcription factor: Mus musculus prostate specific ets transcription factor (Pse-pending), mRNA |
| Length: | 103 |
| Pfam Domains: | 17-101 Ets-domain |
| Sequence: (in bold interface residues) | 1 EGWTDGEVDSSCSGQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWG 60 61 VRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPV |
| Interface Residues: | 13, 71, 72, 74, 75, 76, 78, 79, 94 |
| 3D-footprint Homologues: | 3zp5_A, 4uno_A, 3jtg_A, 1dux_F, 7jsa_J, 8ee9_F, 4mhg_A, 2stt_A, 4l18_B, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A, 1bc8_C |
| Binding Motifs: | UP00038A_1 vyrcATCCGGaTwyty UP00406A_1 syrcwwCCGGwwyytb UP00038A_2 rwbwAcATCCTAkwar |
| Binding Sites: | AAACCGGA AACCGGAT ACATCCGG ACCCGGAT ACCGGAAC ACCGGATG AGATCCGG AGCCGGAT ATATCCGG ATCCGGAA ATCCGGGA CATCCGGA CATCCGGG CCCGGAAC CCCGGATA CCGGATAC CCGGATCC CCGGATGC TATCCGGA GATCCGGA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.