Transcription Factor

						

			
Accessions: 4bqa_A (3D-footprint 20231221)

			
Names: ETS2_HUMAN, PROTEIN C-ETS-2
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P15036
Length: 132
Pfam Domains:    35-116 Ets-domain
Sequence: 
(in bold interface residues)		   1 MSFKDYIQERSDPVEQGKPVIPAAVLAGFTGSGPIQLWQFLLELLSDKSCQSFISWTGDG   60
  61 WEFKLADPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTSGKRYVYRFVCDLQN  120
 121 LLGFTPEELHAI
Interface Residues: 32, 67, 69, 70, 73, 81, 82, 87, 88, 90, 91, 92, 94, 95, 109
3D-footprint Homologues: 3zp5_A, 2wbs_A, 5hdn_C, 7jsa_J, 1dux_F, 4uno_A, 3jtg_A, 8ee9_F, 2stt_A, 4mhg_A, 4iri_A, 4l18_B, 1yo5_C, 5d5v_B, 1awc_A, 4lg0_B, 4bqa_A, 1bc8_C
Binding Motifs: 4bqa_A tTCCg
4bqa_ADG TTCCGnnnnCGGAAGnnnnCTTCCG
Binding Sites: 4bqa_B
4bqa_C
			
Publications: Newman J.A, Cooper C.D, Aitkenhead H, Gileadi O. Structural insights into the autoregulation and cooperativity of the human transcription factor ets-2. The Journal of biological chemistry 290:8539-49 (2015). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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