Transcription Factor

Accessions: 6es2_K (3D-footprint 20231221)
Names: Caudal-type homeobox protein 2, CDX-3, CDX2_HUMAN, Homeobox protein CDX-2
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 70
Pfam Domains: 2-57 Homeobox domain
Sequence:
(in bold interface residues)
1 DKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKINK 60
61 KKLQQQQQQQ
Interface Residues: 2, 3, 4, 42, 43, 45, 46, 49, 50, 53, 54, 55, 56, 57
3D-footprint Homologues: 1jgg_B, 3lnq_A, 1nk2_P, 1zq3_P, 2ld5_A, 7q3o_C, 6es3_K, 1b72_A, 4xrs_G, 3d1n_M, 2hos_A, 1ig7_A, 5zfz_A, 4cyc_A, 2d5v_B, 5flv_I, 1puf_A, 5zjt_E, 3a01_E, 2h1k_B, 7psx_B, 2lkx_A, 6a8r_A, 3cmy_A, 2hdd_A, 1fjl_B, 5jlw_D, 3rkq_B, 2r5y_A, 7xrc_C, 2xsd_C, 1e3o_C, 1au7_A, 1le8_A, 1o4x_A, 1le8_B, 1du0_A, 3l1p_A, 8g87_X, 4qtr_D, 1mnm_C, 5hod_A, 1puf_B, 1k61_B, 4xrm_B, 6m3d_C
Binding Motifs: 6es2_K tTTatng
Binding Sites: 6es2_A
6es2_D
Publications: Morgunova E, Yin Y, Das PK, Jolma A, Zhu F, Popov A, Xu Y, Nilsson L, Taipale J. Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima. Elife : (2018). [Pubmed]
Related annotations: PaperBLAST

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