Transcription Factor
| Accessions: | POU2F2_DBD (HumanTF 1.0) |
| Names: | Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, Oct-2, Octamer-binding protein 2, Octamer-binding transcription factor 2, OTF-2, PO2F2_HUMAN, POU domain, class 2, transcription factor 2, POU2F2 |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Uniprot: | P09086 |
| Notes: | Ensembl ID: ENSG00000028277; DNA-binding domain sequence; TF family: homeodomain+POU; Clone source: Megaman |
| Length: | 204 |
| Pfam Domains: | 23-96 Pou domain - N-terminal to homeobox domain 125-181 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MADPHLSHPQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYG 60 61 NDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGL 120 121 PGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEK 180 181 RINPCSAAPMLPSPGKPASYSPHM |
| Interface Residues: | 48, 64, 65, 66, 67, 69, 70, 76, 80, 125, 126, 127, 128, 166, 167, 169, 170, 173, 174, 176, 177, 178, 181 |
| 3D-footprint Homologues: | 8bx1_A, 7u0g_M, 3d1n_M, 2xsd_C, 1o4x_A, 1e3o_C, 7xrc_C, 8g87_X, 1au7_A, 1fjl_B, 1ig7_A, 8ejp_B, 3cmy_A, 1puf_A, 8pmf_A, 6a8r_A, 4cyc_A, 1zq3_P, 1nk2_P, 3lnq_A, 2lkx_A, 7q3o_C, 2ld5_A, 9b8u_A, 8ik5_C, 1b72_A, 4xrs_G, 3a01_E, 8osb_E, 3rkq_B, 8eml_B, 2r5y_A, 7psx_B, 5hod_A, 5jlw_D, 1le8_A, 6es3_K, 4qtr_D, 6fqp_B, 1du0_A, 5zjt_E, 1jgg_B, 6fqq_E, 5flv_I |
| Binding Motifs: | POU2F2_DBD_1 wTATGcwAATk POU2F2_DBD_2 hwTrmATATkCAwa |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Related annotations: | PaperBLAST |
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