Transcription Factor
| Accessions: | croc (DrosophilaTF 1.1), T082670_1.02 (CISBP 1.02) |
| Names: | CROC_DROME, FKH protein FD1, Fork head domain-containing protein crocodile, croc, T082670_1.02; |
| Organisms: | Drosophila melanogaster |
| Libraries: | DrosophilaTF 1.1 1, CISBP 1.02 2 1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed] 2 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] |
| Notes: | family:Forkhead |
| Length: | 508 |
| Pfam Domains: | 70-165 Fork head domain |
| Sequence: (in bold interface residues) | 1 MHTLFSDQNSFTRHYAQTAAGYGSASAVAAASSASAAAAAHYAYDQYSRYPYSASAYGLG 60 61 APHQNKEIVKPPYSYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSIRH 120 121 NLSLNECFVKVARDDKKPGKGSYWTLDPDSYNMFDNGSFLRRRRRFKKKDVMREKEEAIK 180 181 RQAMMNEKLAEMKPLKLMTNGILEAKHMAAHAAHFKKEPLMDLGCLSGKEVSHAAMLNSC 240 241 HDSLAQMNHLAGGGVEHPGFTVDSLMNVYNPRIHHSAYPYHLNEDNLATVASSQMHHVHH 300 301 AAAAHHAQQLQRHVAHVAHPLTPGGQGAGGQSSGHSPTTISTPHGPAHGGWYTPETPPSE 360 361 PVPHNGQQGTPTHPGHNNNNSSSVLNHNGVGNGGGGGGGGGGGSSSVLTSSPTSALGFRD 420 421 MIFEQNQSCQLDTGSPTGSLQSASPPASASVAAASAAAAAAVISSHHHHHHHHAALSGNL 480 481 GQLGQLSNLSHYRPHVGHYQEYGIKYGV |
| Interface Residues: | 110, 113, 115, 116, 117, 119, 120, 121, 123, 124, 133, 140, 162, 165, 461, 473, 474, 477 |
| 3D-footprint Homologues: | 3l2c_A, 7vox_H, 2hdc_A, 3g73_A, 6ako_C, 7yzg_A, 7tdw_A, 7yz7_A, 6el8_A, 2uzk_A, 7tdx_A, 2a07_J, 7yzb_A, 6nce_A, 3co6_C, 7vou_C, 2c6y_A, 7yze_A, 7cby_C, 3qrf_G, 4s2q_D |
| Binding Motifs: | croc rTAAAA M2546_1.02 wwaarTAAATAkwwkr |
| Binding Sites: | croc_1 croc_10 croc_11 croc_12 croc_13 croc_14 croc_15 croc_2 croc_3 croc_4 croc_5 croc_6 croc_7 croc_8 croc_9 |
| Publications: | Haecker U., Kaufmann E., Hartmann C., Juergens G., Knoechel W., Jaeckle H. The Drosophila fork head domain protein crocodile is required for the establishment of head structures. EMBO J. 14:5306-5317 (1995). [Pubmed] |
| Related annotations: | PaperBLAST |
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