Transcription Factor

Accessions: 3zp5_A (3D-footprint 20231221)
Names: FEV_HUMAN, Fifth Ewing variant protein, PC12 ETS domain-containing transcription factor 1, PC12 ETS factor 1, Pet-1, PROTEIN FEV
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q99581
Length: 92
Pfam Domains: 3-85 Ets-domain
Sequence:
(in bold interface residues)
1 SGQIQLWQFLLELLADRANAGCIAWEGGHGEFKLTDPDEVARRWGERKSKPNMNYDKLSR 60
61 ALRYYYDKNIMSKVHGKRYAYRFDFQGLAQAC
Interface Residues: 1, 56, 57, 59, 60, 61, 63, 64, 78
3D-footprint Homologues: 3zp5_A, 7jsa_J, 8ee9_F, 4mhg_A, 2stt_A, 4uno_A, 3jtg_A, 1dux_F, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A, 1bc8_C, 4l18_B
Binding Motifs: 3zp5_A tCCG
Binding Sites: 3zp5_G
3zp5_C
Publications: Cooper C.D, Newman J.A, Aitkenhead H, Allerston C.K, Gileadi O. Structures of the Ets Domains of Transcription Factors ETV1, ETV4, ETV5 and FEV: Determinants of DNA Binding and Redox Regulation by Disulfide bond formation. The Journal of biological chemistry : (2015). [Pubmed]
Related annotations: PaperBLAST

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