Transcription Factor

Accessions: 2o61_B (3D-footprint 20231221)
Names: DNA-binding factor KBF1, EBP-1, NFKB1_HUMAN, Nuclear factor NF-kappa-B p105 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P19838
Length: 314
Pfam Domains: 6-204 Rel homology domain (RHD)
Sequence:
(in bold interface residues)
1 MDGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQ 60
61 LVTNGKNIHLHAHSLVGKHCEDGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMT 120
121 EACIRGYNPGLLVHPDLAYLQAEGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTA 180
181 FLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKD 240
241 DIQIRFYEEEENGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSD 300
301 LETSEPKPFLYYPE
Interface Residues: 18, 20, 21, 23, 24, 26, 27, 28, 205, 207, 236, 269, 296, 297
3D-footprint Homologues: 1gji_A, 2ram_A, 1nfk_A, 7cli_B, 1a3q_A, 2o61_A, 1p7h_L
Binding Motifs: 2o61_AB GGAGAnnTTAAnnTGGGAAnTTCCTC
Binding Sites: 2o61_E
2o61_F
Publications: Panne D, Maniatis T, Harrison S.C. An atomic model of the interferon-beta enhanceosome. Cell 129:1111-23 (2007). [Pubmed]
Related annotations: PaperBLAST

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