Transcription Factor

Accessions: UP00096A (UniPROBE 20160601)
Names: AA407916, AW259412, AW540933, Sox-13, SOX-13 protein, Sox13, SRY-box containing gene 13
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q04891
Description: SRY-box containing gene 13: nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100, mRNA (cDNA clone MGC:35934 IMAGE:3672913), complete cds
Length: 101
Pfam Domains: 17-85 HMG (high mobility group) box
18-78 Domain of unknown function (DUF1898)
Sequence:
(in bold interface residues)
1 DMDGSRHFSESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTN 60
61 QEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCVVEGRRL
Interface Residues: 19, 22, 24, 25, 28, 32, 43, 44, 45, 48, 86
3D-footprint Homologues: 4y60_C, 2gzk_A, 1j5n_A, 6jrp_D, 2lef_A, 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 4s2q_D, 1qrv_A, 3tmm_A, 1hry_A, 3tq6_B, 1ckt_A
Binding Motifs: UP00096A_1 wtwrgAACAATwwwtw
UP00096A_2 rtrytGGgtGGGwawwt
Binding Sites: AAAACAAT
AAACAATT
AACAATAA
AACAATAT
AACAATTA
AACAATTG
AATTAATA
AATTGTCT
ACAACAAT
ACAATTAA
ACAATTGT
AGAACAAT
AGACAATA
ATTGTTCA
ATTGTTCC
ATTGTTCG
ATTGTTTC
GAACAATA
TAACAATA
ACAATAAA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.