Transcription Factor

Accessions: 3wgi_C (3D-footprint 20231221), 3wgi_D (3D-footprint 20231221)
Names: D5KM69_THEET, Redox-sensing transcriptional repressor rex
Organisms: Thermoanaerobacter ethanolicus JW 200
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: D5KM69
Length: 217
Pfam Domains: 3-51 Putative DNA-binding protein N-terminus
79-176 CoA binding domain
Sequence:
(in bold interface residues)
1 KTIVSMAVIRRLPRYHRYLEELLKNDVKRISSRELSEKMGVTASQIRQDLNNFGGFGQQG 60
61 YGYNVEELYNNLTKILGLDKTYNTIIIGAGNLGQAIANYTSFEKSGFNLKGIFDINPRLF 120
121 GLKIRDVEVMDVETVEDFIARNKIDIGILCIPKDNAQYTADRLVRAGIKAIWNFLPIDLK 180
181 VPDDVILENVHLSDSLFTVSYRLNEEELFKKLKGETA
Interface Residues: 32, 33, 42, 43, 44, 45, 47, 48, 51, 52, 59, 61
3D-footprint Homologues: 4wwc_B, 4u0y_B, 3ikt_B, 3ket_A, 7wb3_B, 3wgi_D
Binding Motifs: 3wgi_CD TTGTTAAnnnnTTAACAA
3wgi_D TTGTTAA
Binding Sites: 3wgi_G / 3wgi_H
Publications: Zheng Y, Ko TP, Sun H, Huang CH, Pei J, Qiu R, Wang AH, Wiegel J, Shao W, Guo RT. Distinct structural features of Rex-family repressors to sense redox levels in anaerobes and aerobes. J Struct Biol 188:195-204 (2014). [Pubmed]
Related annotations: PaperBLAST

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