Transcription Factor

Accessions: Q9SLH1 (JASPAR 2024), T07980 (AthalianaCistrome v4_May2016)
Names: Myb domain protein 81, Myb family transcription factor, Q9SLH1_ARATH, AT2G26960, MYB81, T07980;
Organisms: Arabidopsis thaliana
Libraries: JASPAR 2024 1, AthalianaCistrome v4_May2016 2
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
Notes: ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq, family:MYB
Length: 427
Pfam Domains: 22-69 Myb-like DNA-binding domain
25-85 Myb-like DNA-binding domain
75-118 Myb-like DNA-binding domain
Sequence:
(in bold interface residues)
1 MGKVRQDSGSDDDNSIKKSFTKGPWTQAEDNLLIAYVDKHGDGNWNAVQNNSGLSRCGKS 60
61 CRLRWVNHLRPDLKKGAFTEKEEKRVIELHALLGNKWARMAEELPGRTDNEIKNFWNTRL 120
121 KRLQRLGLPVYPDEVREHAMNAATHSGLNTDSLDGHHSQEYMEADTVEIPEVDFEHLPLN 180
181 RSSSYYQSMLRHVPPTNVFVRQKPCFFQPPNVYNLIPPSPYMSTGKRPREPETAFPCPGG 240
241 YTMNEQSPRLWNYPFVENVSEQLPDSHLLGNAAYSSPPGPLVHGVENFEFPSFQYHEEPG 300
301 GWGADQPNPMPEHESDNTLVQSPLTAQTPSDCPSSSLYDGLLESVVYGSSGEKPATDTDS 360
361 ESSLFQSFTPANENITGKTCFLTLYALHALHCLCNQFKKSPLLHLHDKLNWCNKFRFNSF 420
421 KSGTHIL
Interface Residues: 22, 57, 58, 59, 60, 62, 63, 67, 68, 109, 110, 113, 114, 117, 118, 119
3D-footprint Homologues: 3osg_A, 1vfc_A, 2kdz_A, 6kks_A, 1mse_C, 3zqc_A, 7xur_A
Binding Motifs: M0529 / MA1175.1 sTAACcGwwTy
M0553 wyystAACcGtwwy
MA1175.2 TAACcGwwT
Binding Sites: MA1175.1.1 / MA1175.1.2
MA1175.1.10 / MA1175.1.19
MA1175.1.11
MA1175.1.12
MA1175.1.13
MA1175.1.14
MA1175.1.15
MA1175.1.16
MA1175.1.17
MA1175.1.18 / MA1175.1.9
MA1175.1.20
MA1175.1.3
MA1175.1.4
MA1175.1.5
MA1175.1.6
MA1175.1.7
MA1175.1.8
MA1175.2.9
MA1175.2.3
MA1175.2.1
MA1175.2.10 / MA1175.2.20
MA1175.2.11
MA1175.2.12
MA1175.2.13
MA1175.2.14
MA1175.2.15
MA1175.2.16
MA1175.2.17
MA1175.2.18
MA1175.2.19
MA1175.2.2
MA1175.2.4
MA1175.2.5
MA1175.2.6
MA1175.2.7
MA1175.2.8
Publications: Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Related annotations: PaperBLAST

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