Transcription Factor

Accessions: 1an2_A (3D-footprint 20231221)
Names: bHLHd4, Class D basic helix-loop-helix protein 4, MAX_HUMAN, Myc-associated factor X, Protein max, TRANSCRIPTION FACTOR MAX (TF MAX)
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P61244
Length: 86
Pfam Domains: 3-53 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 ADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTH 60
61 QQDIDDLKRQNALLEQQVRALEKARS
Interface Residues: 4, 6, 7, 8, 10, 11, 14, 15, 19, 39
3D-footprint Homologues: 1a0a_B, 7z5k_B, 1an4_A, 7ssa_L, 5i50_B, 1am9_A, 8osl_O, 7d8t_A, 4zpk_A, 7xi3_A, 5nj8_D, 7f2f_B, 5eyo_A, 7xq5_A, 5v0l_A, 4h10_A, 7rcu_E, 5gnj_I, 6g1l_A, 4h10_B
Binding Motifs: 1an2_A CGTg
Binding Sites: 1an2_B
Publications: Ferre-D'Amare A. E., Prendergast G. C., Ziff E. B., Burley S. K. Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain. Nature 363:38-45 (1993). [Pubmed]
Related annotations: PaperBLAST

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