Transcription Factor
| Accessions: | Q6PDB4 (JASPAR 2024) |
| Names: | ZN880_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q6PDB4 |
| Length: | 577 |
| Pfam Domains: | 8-47 KRAB box 205-223 Zinc-finger double domain 211-232 C2H2-type zinc finger 212-234 C2H2-type zinc finger 212-234 Zinc finger, C2H2 type 226-250 Zinc-finger double domain 239-260 C2H2-type zinc finger 240-262 C2H2-type zinc finger 240-262 Zinc finger, C2H2 type 255-279 Zinc-finger double domain 267-280 C2H2-type zinc finger 268-290 Zinc finger, C2H2 type 268-288 C2H2-type zinc finger 282-306 Zinc-finger double domain 295-306 C2H2-type zinc finger 296-318 Zinc finger, C2H2 type 296-318 C2H2-type zinc finger 310-334 Zinc-finger double domain 323-342 C2H2-type zinc finger 324-346 Zinc finger, C2H2 type 339-362 Zinc-finger double domain 351-363 C2H2-type zinc finger 352-374 Zinc finger, C2H2 type 352-374 C2H2-type zinc finger 366-391 Zinc-finger double domain 379-391 C2H2-type zinc finger 380-402 Zinc finger, C2H2 type 380-402 C2H2-type zinc finger 395-417 Zinc-finger double domain 407-426 C2H2-type zinc finger 408-430 Zinc finger, C2H2 type 408-430 C2H2-type zinc finger 423-447 Zinc-finger double domain 435-458 C2H2-type zinc finger 436-458 C2H2-type zinc finger 450-475 Zinc-finger double domain 464-484 C2H2-type zinc finger 464-474 C2H2-type zinc finger 464-486 Zinc finger, C2H2 type 478-503 Zinc-finger double domain 491-503 C2H2-type zinc finger 492-512 C2H2-type zinc finger 492-514 Zinc finger, C2H2 type 506-531 Zinc-finger double domain 520-542 Zinc finger, C2H2 type 520-542 C2H2-type zinc finger 520-531 C2H2-type zinc finger 535-559 Zinc-finger double domain 548-558 C2H2-type zinc finger 548-570 Zinc finger, C2H2 type 548-568 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MLRRGHLAFRDVAIEFPQEEWKCLDPAQRTLYREVMVENYRNLVFLGICLPDLSVISMLE 60 61 QRRDPRNLQSEVKIANNPGGRECIKGVNAESSSKLGSNAGNKSLKNQLGLTFQLHLSELQ 120 121 LFQAERNISGCKHVEKPINNSLVSPLQKIYSSVKSHILNKYRNDFDDSPFLPQEQKAQIR 180 181 EKPCECNEHGKAFRVSSRLANNQVIHTADNPYKCNECDKVFSNSSNLVQHQRIHTGEKPY 240 241 KCHECGKLFNRISLLARHQRIHTGEKPYKCHECGKVFTQNSHLANHHRIHTGEKPYKCNE 300 301 CGKVFNRNAHLARHQKIHSGEKPYKCKECGKAFSGGSGLTAHLVIHTGEKLYKCNKCGKV 360 361 FNRNAHLTRHQRIHTGEKPYECKECGKVFRHKFCLTNHHRMHTGEQPYKCNECGKAFRDC 420 421 SGLTAHLLIHTGEKPYKCKECAKVFRHRLSLSNHQRFHTGEKPYRCDECGKDFTRNSNLA 480 481 NHHRIHTGEKPYKCSECHKVFSHNSHLARHRQIHTGEKSYKCNECGKVFSHKLYLKKHER 540 541 IHTGEKPYRCHECGKDFTRNSNLANHHRIHTGEKPYR |
| Interface Residues: | 195, 197, 198, 201, 205, 222, 223, 224, 225, 226, 228, 229, 231, 232, 235, 251, 252, 253, 254, 257, 261, 278, 279, 280, 281, 282, 285, 306, 307, 308, 309, 310, 312, 313, 317, 335, 336, 337, 338, 340, 341, 362, 363, 364, 365, 366, 369, 372, 390, 391, 393, 394, 397, 403, 408, 417, 419, 420, 421, 422, 424, 425, 426, 429, 446, 447, 448, 449, 450, 451, 453, 454, 456, 474, 475, 476, 477, 478, 481, 503, 505, 506, 508, 509, 530, 531, 533, 534, 537, 559, 560, 561, 562, 565 |
| 3D-footprint Homologues: | 8ssu_A, 7w1m_H, 7n5w_A, 5ei9_F, 6blw_A, 5k5l_F, 8h9h_G, 7ysf_A, 2jpa_A, 5kl3_A, 7txc_E, 6ml4_A, 4x9j_A, 2gli_A, 1f2i_J, 5kkq_D, 1g2f_F, 1llm_D, 6u9q_A, 3uk3_C, 5k5i_A, 5v3j_F, 8ssq_A, 2wbs_A, 5yj3_D, 5yel_A, 1ubd_C, 6jnm_A, 6a57_A, 1tf6_A, 2kmk_A, 4m9v_C, 2drp_D, 8gn3_A, 7y3m_I, 1tf3_A, 6e94_A, 2lt7_A, 8cuc_F, 7y3l_A |
| Binding Motifs: | UN0665.1 gcaCTyTCCCmy UN0665.2 gcaCTyTCCC |
| Binding Sites: | UN0665.1.1 UN0665.1.10 / UN0665.1.14 UN0665.1.11 / UN0665.1.16 UN0665.1.12 / UN0665.1.19 UN0665.1.13 / UN0665.1.20 UN0665.1.14 UN0665.1.15 UN0665.1.16 UN0665.1.17 UN0665.1.18 UN0665.1.19 UN0665.1.2 UN0665.1.20 UN0665.1.3 UN0665.1.4 UN0665.1.5 UN0665.1.6 UN0665.1.7 UN0665.1.8 UN0665.1.13 / UN0665.1.9 UN0665.1.10 UN0665.1.11 UN0665.1.12 UN0665.1.15 UN0665.1.17 UN0665.1.18 UN0665.1.7 UN0665.1.8 UN0665.1.9 UN0665.2.1 UN0665.2.10 UN0665.2.11 / UN0665.2.14 / UN0665.2.15 / UN0665.2.3 / UN0665.2.4 / UN0665.2.5 UN0665.2.12 UN0665.2.13 UN0665.2.16 UN0665.2.17 UN0665.2.18 UN0665.2.19 UN0665.2.2 UN0665.2.20 UN0665.2.6 UN0665.2.7 UN0665.2.8 UN0665.2.9 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.