Transcription Factor

						

			
Accessions: T134720_1.02 (CISBP 1.02)

			
Names: nhr-65, T134720_1.02;
Organisms: Caenorhabditis elegans
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Nuclear receptor
Length: 398
Pfam Domains:     12-73 Zinc finger, C4 type (two domains)
  164-382 Ligand-binding domain of nuclear hormone receptor
Sequence: 
(in bold interface residues)		   1 MELEPCSSSPERCKVCGDTGNGMHFGAFTCRACAAFFRRAASRKFLRKCENHLIFALKCK   60
  61 NCRLQRCYEAGMSSENFQFCRDLIGAKGAIPKLKVPKSFEQTVGRPYFVLQCDPEVLFLR  120
 121 RNIIDCVPLLEKAEKLIEFGSESPVFSKNRLLKLAQGLQQFQDAKSNQVKFVQKMGQKEI  180
 181 MSFFETDFLCATKWFTYLDEFQFLDKNQQLTLMQGIWHVWSRLHKLAVSAMGRRRGICDK  240
 241 NTVMVSHQNEFAVCDLNEIEVDMSWCTNFSNEQMRYFLDTSHDSYVYQVMDEMLGLKPND  300
 301 VELSYMMCQLCLQYAGQRFQGEILEFCEKMLGFLADDLHSYYVKQLRMPNYAARLAKLMK  360
 361 INNRIKESVLKTRQRQQIAELFNVWTVDFSHPEFFRDA
Interface Residues: 21, 22, 24, 25, 31, 32, 34, 35, 38, 39, 57, 79, 81, 83, 86, 87, 89
3D-footprint Homologues: 6fbq_A, 6l6q_B, 7wnh_D, 1lo1_A, 3g9m_B, 1a6y_A, 4oln_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 7xvn_C, 4iqr_B, 2han_A, 1hcq_E, 8cef_H, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 8hbm_B, 2nll_B, 1lat_A, 7xv6_B, 4hn5_B, 8rm6_A, 5emc_A, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E, 4tnt_B, 5e69_A
Binding Motifs: M1483_1.02 wwaTTTGTgtyc
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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