Transcription Factor

Accessions: UP00047A (UniPROBE 20160601)
Names: c-Krox, Kruppel-related zinc finger protein cKrox, MGC102577, T-helper-inducing POZ/Kruppel-like factor, Thpok, Vzinc finger and BTB domain containing 7B, Zbtb7b, Zfp-67, Zfp67, Zinc finger and BTB domain-containing protein 7B, Zinc finger protein 67, Zinc finger protein Th-POK
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Description: Vzinc finger and BTB domain containing 7B: Mus musculus hypothetical gene supported by NM_009565
Length: 139
Pfam Domains: 33-55 Zinc-finger double domain
44-66 C2H2-type zinc finger
44-66 Zinc finger, C2H2 type
59-83 Zinc-finger double domain
72-94 C2H2-type zinc finger
72-94 Zinc finger, C2H2 type
86-110 Zinc-finger double domain
100-120 C2H2-type zinc finger
100-120 Zinc finger, C2H2 type
100-122 Zinc-finger of C2H2 type
Sequence:
(in bold interface residues)
1 DGQDKLVRKRRSQMPQECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLK 60
61 IHMRKHTGERPYSCPHCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRHLK 120
121 GQNCLEVRTRRRRKDDVAA
Interface Residues: 4, 5, 9, 12, 13, 26, 27, 28, 29, 30, 32, 33, 35, 36, 37, 39, 44, 54, 55, 56, 57, 58, 60, 61, 62, 65, 82, 83, 84, 85, 86, 87, 88, 89, 90, 93, 110, 111, 112, 113, 114, 116, 117
3D-footprint Homologues: 2i13_A, 1yuj_A, 7y3l_A, 7n5w_A, 3uk3_C, 8cuc_F, 8ssu_A, 6ml4_A, 5v3j_F, 6blw_A, 5kkq_D, 1f2i_J, 5ei9_F, 5k5i_A, 8ssq_A, 7w1m_H, 1llm_D, 8h9h_G, 7eyi_G, 7y3m_I, 6e94_A, 7ysf_A, 6wmi_A, 1tf6_A, 2jpa_A, 1ubd_C, 2kmk_A, 1tf3_A, 6jnm_A, 5k5l_F, 4x9j_A, 1mey_C, 6u9q_A, 5yel_A, 7txc_E, 5kl3_A, 1g2f_F, 5und_A, 2gli_A, 4m9v_C, 2lt7_A, 6a57_A, 8gn3_A, 2wbs_A, 2drp_D, 5yj3_D
Binding Motifs: UP00047A_1 rrgCCCCCCwaawat
UP00047A_2 ywkrvGACCACCaktry
Binding Sites: AAGCCCCC
ACCCCCCA
AGACCCCC
AGCCCCCT
AGGGGGGG
AGGGGGTC
ATGGGGGG
CCCCCCAA
CCCCCCCA
CCCCCCCC
CCCCCCTC
CGACCCCC
CGCCCCCC
CGGGGGGC
CGGGGGTC
GACCCCCA
GACCCCCC
GCCCCCCA
GCCCCCCC
GGACCCCC
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.