Transcription Factor

Accessions: 5ze0_N (3D-footprint 20231221)
Names: High mobility group protein 1, High mobility group protein B1, HMG-1, HMGB1 A-B box, HMGB1_MOUSE
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P63158
Length: 118
Pfam Domains: 1-63 Domain of unknown function (DUF1898)
4-64 HMG (high mobility group) box
64-118 HMG (high mobility group) box
64-117 Domain of unknown function (DUF1898)
Sequence:
(in bold interface residues)
1 RGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKAKEKGKFEDMAKADKARYE 60
61 REMKRPPSAFFLFCSEYRPKIKGEIGDVAKKLGEMWNNTDDKQPYEKKAAKLKEKYEK
Interface Residues: 5, 7, 8, 11, 29, 33, 65, 68, 70, 71, 74, 78, 85, 86, 89
3D-footprint Homologues: 1j5n_A, 1ckt_A, 7m5w_A, 1qrv_A, 4s2q_D, 2gzk_A, 4y60_C, 3f27_D, 6jrp_D, 1o4x_B, 3u2b_C, 1hry_A
Binding Motifs: 5ze0_N CTnnnnnnnnacTT
Binding Sites: 5ze0_G
5ze0_M
Publications: Kim MS, Chuenchor W, Chen X, Cui Y, Zhang X, Zhou ZH, Gellert M, Yang W. Cracking the DNA Code for V(D)J Recombination. Mol Cell 70:358-370 (2018). [Pubmed]
Related annotations: PaperBLAST

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