Transcription Factor
| Accessions: | Elf5_DBD (HumanTF 1.0), UP00409A (UniPROBE 20160601) |
| Names: | E74-like factor 5, Elf5, ELF5_MOUSE, ETS-related transcription factor Elf-5, ESE-2, ESE-5 |
| Organisms: | Mus musculus |
| Libraries: | HumanTF 1.0 1, UniPROBE 20160601 2 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] 2 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q8VDK3 |
| Description: | E74-like factor 5: ETS-related transcription factor Elf-5 |
| Notes: | Ensembl ID: ENSMUSG00000027186; DNA-binding domain sequence; TF family: ETS; Clone source: Hughes lab. |
| Length: | 109 |
| Pfam Domains: | 18-99 Ets-domain |
| Sequence: (in bold interface residues) | 1 SGIKSQDCHSRTSLQSSHLWEFVRDLLLSPEENCGILEWEDREQGIFRVVKSEALAKMWG 60 61 QRKKNDRMTYEKLSRALRYYYKTGILERVDRRLVYKFGKNAHGWQEEKL |
| Interface Residues: | 71, 72, 74, 75, 76, 78, 79, 92 |
| 3D-footprint Homologues: | 4mhg_A, 2stt_A, 4uno_A, 3jtg_A, 1dux_F, 7jsa_J, 3zp5_A, 8ee9_F, 4iri_A, 1bc8_C, 4l18_B, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A |
| Binding Motifs: | UP00409A_1 kwAcsmGGAAGTwr Elf5_DBD acsmGGAArtr |
| Binding Sites: | AACTTCCG AACTTCCT AAGGAAAT AAGGAAGT ACCAGGAA ACCCGGAA ACGGAAGT ACTTCCGC ACTTCCGG ACTTCCTC ACTTCCTG AGGAAGTA ATTTCCGG CACTTCCG CCCGGAAA CCCGGAAG CGGAAGTA CGGAAGTC GGAAGTAA TTCCGGAA |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed] |
| Related annotations: | PaperBLAST |
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