Transcription Factor
| Accessions: | Q86TJ5 (JASPAR 2024) |
| Names: | ZN554_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q86TJ5 |
| Length: | 538 |
| Pfam Domains: | 45-85 KRAB box 310-334 Zinc-finger double domain 324-346 C2H2-type zinc finger 324-346 Zinc finger, C2H2 type 324-344 C2H2-type zinc finger 338-363 Zinc-finger double domain 351-374 C2H2-type zinc finger 352-374 C2H2-type zinc finger 352-374 Zinc finger, C2H2 type 367-390 Zinc-finger double domain 380-400 C2H2-type zinc finger 380-402 Zinc finger, C2H2 type 382-402 C2H2-type zinc finger 394-417 Zinc-finger double domain 407-430 C2H2-type zinc finger 408-430 C2H2-type zinc finger 408-430 Zinc finger, C2H2 type 426-446 Zinc-finger double domain 435-458 C2H2-type zinc finger 436-458 C2H2-type zinc finger 436-458 Zinc finger, C2H2 type 450-474 Zinc-finger double domain 463-486 C2H2-type zinc finger 464-486 C2H2-type zinc finger 464-486 Zinc finger, C2H2 type 478-502 Zinc-finger double domain 492-515 C2H2-type zinc finger 492-514 C2H2-type zinc finger 492-514 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MVTCAHLGRRARLPAAQPSACPGTCFSQEERMAAGYLPRWSQELVTFEDVSMDFSQEEWE 60 61 LLEPAQKNLYREVMLENYRNVVSLEALKNQCTDVGIKEGPLSPAQTSQVTSLSSWTGYLL 120 121 FQPVASSHLEQREALWIEEKGTPQASCSDWMTVLRNQDSTYKKVALQEEPASGINMIKLI 180 181 REDGGWKQLEDSHEDPQGLLSQKASLHVVAVPQEKATAWHGFGENGNLSPALVLSQGSSK 240 241 GNHLCGSELDITSLASDSVLNHHQLGYADRRPCESNECGNAIRQNSHFIQHGGKMFVYLE 300 301 NGQSLNHGMALTIHNKINTAEKPFECHQCGKVFNRRHSLSEHQRIHTGEKPYECQECGRA 360 361 FTHSSTLTRHLRTHTGEKPYGCGECGKAFNRISSLTQHQRIHTGEKPYKCEDCGKSFCQS 420 421 SYLILHKRTHTGEKPYECSECGKAFSDRSSLNQHERTHTGENPYECKQCGRAFSQRSSLV 480 481 RHERTHTGEKPYRCQECGKAFSQSSSLVTHQKTHSSQKTYKIIDCGKAFYQNRHLIGY |
| Interface Residues: | 334, 335, 337, 338, 341, 345, 352, 362, 363, 364, 365, 366, 368, 369, 390, 391, 392, 393, 394, 396, 397, 400, 401, 418, 419, 420, 421, 422, 424, 425, 426, 427, 428, 431, 446, 447, 448, 449, 450, 451, 452, 453, 454, 457, 474, 475, 476, 477, 478, 480, 481, 503, 504, 505, 506, 509, 515, 529, 531, 533, 534 |
| 3D-footprint Homologues: | 1tf3_A, 6jnm_A, 4x9j_A, 8ssu_A, 1tf6_A, 5v3j_F, 8ssq_A, 7w1m_H, 5yel_A, 6a57_A, 2kmk_A, 2gli_A, 8gn3_A, 1llm_D, 6ml4_A, 2drp_D, 2lt7_A, 7ysf_A, 1ubd_C, 1f2i_J, 6blw_A, 7y3l_A, 5kkq_D, 5ei9_F, 1g2f_F, 5k5i_A, 4m9v_C, 6e94_A, 7y3m_I, 2jpa_A, 8cuc_F, 7n5w_A, 3uk3_C, 5k5l_F, 6u9q_A, 5yj3_D, 5kl3_A, 8h9h_G, 2wbs_A, 7txc_E |
| Binding Motifs: | UN0630.1 ssGCAGAGCcv UN0630.2 GCAGAGC |
| Binding Sites: | UN0630.1.1 / UN0630.1.5 UN0630.1.10 UN0630.1.11 UN0630.1.12 / UN0630.1.20 UN0630.1.13 UN0630.1.14 / UN0630.1.15 UN0630.1.16 / UN0630.1.18 UN0630.1.17 UN0630.1.19 UN0630.1.2 / UN0630.1.8 UN0630.1.12 / UN0630.1.3 UN0630.1.13 / UN0630.1.4 UN0630.1.5 UN0630.1.15 / UN0630.1.6 UN0630.1.18 / UN0630.1.7 UN0630.1.19 / UN0630.1.8 UN0630.1.20 / UN0630.1.9 UN0630.1.1 UN0630.1.10 UN0630.1.11 UN0630.1.14 UN0630.1.16 UN0630.1.17 UN0630.1.2 UN0630.1.3 UN0630.1.4 UN0630.1.6 UN0630.1.7 UN0630.1.9 UN0630.2.1 / UN0630.2.13 / UN0630.2.14 / UN0630.2.15 / UN0630.2.3 UN0630.2.10 / UN0630.2.16 / UN0630.2.18 / UN0630.2.2 / UN0630.2.6 UN0630.2.11 UN0630.2.12 / UN0630.2.20 / UN0630.2.4 / UN0630.2.9 UN0630.2.17 UN0630.2.19 UN0630.2.5 UN0630.2.7 UN0630.2.8 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.