Transcription Factor
| Accessions: | P51523 (JASPAR 2024) |
| Names: | Zinc finger protein 84, Zinc finger protein HPF2, ZNF84_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P51523 |
| Length: | 738 |
| Pfam Domains: | 9-48 KRAB box 203-217 Zinc-finger double domain 206-229 C2H2-type zinc finger 207-229 C2H2-type zinc finger 207-229 Zinc finger, C2H2 type 236-257 Zinc finger, C2H2 type 236-257 C2H2-type zinc finger 237-257 C2H2-type zinc finger 253-273 Zinc-finger double domain 263-285 C2H2-type zinc finger 263-285 Zinc finger, C2H2 type 263-285 C2H2-type zinc finger 278-302 Zinc-finger double domain 290-309 C2H2-type zinc finger 291-313 C2H2-type zinc finger 291-313 Zinc finger, C2H2 type 308-329 Zinc-finger double domain 319-341 Zinc finger, C2H2 type 319-339 C2H2-type zinc finger 321-341 C2H2-type zinc finger 333-358 Zinc-finger double domain 347-369 C2H2-type zinc finger 347-369 C2H2-type zinc finger 347-369 Zinc finger, C2H2 type 362-384 Zinc-finger double domain 376-397 Zinc finger, C2H2 type 377-397 C2H2-type zinc finger 390-412 Zinc-finger double domain 402-425 C2H2-type zinc finger 403-425 Zinc finger, C2H2 type 403-425 C2H2-type zinc finger 418-441 Zinc-finger double domain 433-453 C2H2-type zinc finger 435-453 Zinc finger, C2H2 type 446-470 Zinc-finger double domain 459-481 C2H2-type zinc finger 459-481 C2H2-type zinc finger 459-481 Zinc finger, C2H2 type 474-497 Zinc-finger double domain 486-505 C2H2-type zinc finger 487-509 C2H2-type zinc finger 487-509 Zinc finger, C2H2 type 501-524 Zinc-finger double domain 515-537 C2H2-type zinc finger 515-537 C2H2-type zinc finger 515-537 Zinc finger, C2H2 type 530-553 Zinc-finger double domain 542-565 C2H2-type zinc finger 543-565 C2H2-type zinc finger 543-565 Zinc finger, C2H2 type 558-581 Zinc-finger double domain 570-584 C2H2-type zinc finger 571-593 C2H2-type zinc finger 571-593 Zinc finger, C2H2 type 586-608 Zinc-finger double domain 598-617 C2H2-type zinc finger 599-621 Zinc finger, C2H2 type 599-621 C2H2-type zinc finger 614-636 Zinc-finger double domain 626-647 C2H2-type zinc finger 627-649 Zinc finger, C2H2 type 627-649 C2H2-type zinc finger 642-666 Zinc-finger double domain 655-677 C2H2-type zinc finger 655-677 C2H2-type zinc finger 655-677 Zinc finger, C2H2 type 673-693 Zinc-finger double domain 683-705 Zinc finger, C2H2 type 685-705 C2H2-type zinc finger 698-721 Zinc-finger double domain 711-733 C2H2-type zinc finger 711-733 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MTMLQESFSFDDLSVDFTQKEWQLLDPSQKNLYKDVMLENYSSLVSLGYEVMKPDVIFKL 60 61 EQGEEPWVGDGEIPSSDSPEVWKVDGNMMWHQDNQDKLKIIKRGHECDAFGKNFNLNMNF 120 121 VPLRKSNSEGDLDGLILKHHLDLLIPKGDYGKAESDDFNVFDNFFLHSKPEDTDTWLKYY 180 181 DCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNC 240 241 GKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAF 300 301 SRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKS 360 361 QLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLIN 420 421 HQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRT 480 481 HTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGE 540 541 KPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYE 600 601 CSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSEC 660 661 GKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAF 720 721 SQKSQLINHQRTHTVKKS |
| Interface Residues: | 273, 274, 275, 276, 277, 280, 291, 302, 303, 304, 305, 307, 308, 310, 311, 314, 329, 330, 332, 333, 336, 339, 358, 359, 360, 361, 364, 369, 386, 387, 388, 389, 392, 441, 442, 444, 448, 469, 470, 471, 472, 473, 476, 477, 498, 499, 500, 501, 502, 504, 505, 508, 526, 527, 528, 529, 531, 532, 535, 553, 554, 555, 556, 557, 560, 582, 583, 584, 585, 587, 588, 609, 610, 611, 612, 613, 615, 616, 619, 637, 638, 639, 640, 641, 644, 650, 664, 666, 667, 668, 669, 671, 672, 676, 693, 694, 695, 696, 697, 698, 721, 722, 724, 725, 728 |
| 3D-footprint Homologues: | 1tf3_A, 7y3l_A, 7n5w_A, 4x9j_A, 5ei9_F, 2drp_D, 8h9h_G, 2kmk_A, 7txc_E, 6blw_A, 5yj3_D, 1llm_D, 2jpa_A, 1f2i_J, 2wbs_A, 5kl3_A, 6dta_B, 5k5l_F, 8cuc_F, 7w1m_H, 1ubd_C, 6jnm_A, 1tf6_A, 4m9v_C, 6e94_A, 6a57_A, 8ssq_A, 8ssu_A, 2gli_A, 5v3j_F, 3uk3_C, 5kkq_D, 6u9q_A, 7ysf_A, 7y3m_I, 1g2f_F, 5yel_A, 6ml4_A, 5k5i_A, 2lt7_A, 8gn3_A |
| Binding Motifs: | UN0239.1 TGYCTGTTCAT |
| Binding Sites: | UN0239.1.1 UN0239.1.10 UN0239.1.11 UN0239.1.12 UN0239.1.13 UN0239.1.13 / UN0239.1.14 UN0239.1.15 / UN0239.1.16 UN0239.1.16 / UN0239.1.17 UN0239.1.17 UN0239.1.18 UN0239.1.19 UN0239.1.2 UN0239.1.20 UN0239.1.3 UN0239.1.4 UN0239.1.4 / UN0239.1.5 UN0239.1.6 UN0239.1.7 UN0239.1.8 UN0239.1.9 UN0239.1.14 UN0239.1.15 UN0239.1.18 UN0239.1.19 UN0239.1.2 UN0239.1.20 UN0239.1.5 UN0239.1.8 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.