Transcription Factor

Accessions: P70340 (JASPAR 2024)
Names: Dwarfin-A, Dwf-A, MAD homolog 1, Mad-related protein 1, mMad1, Mothers against decapentaplegic homolog 1, Mothers against DPP homolog 1, Mothers-against-DPP-related 1, SMAD 1, SMAD family member 1, SMAD1_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P70340
Length: 465
Pfam Domains: 31-131 MH1 domain
266-442 MH2 domain
321-402 Interferon-regulatory factor 3
Sequence:
(in bold interface residues)
1 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQ 60
61 PSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEV 120
121 CINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPN 180
181 SHPFPHSPNSSYPNSPGGSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMAQDGSQ 240
241 PMDTNMMAPPLPAEISRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 300
301 DPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 360
361 NYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGW 420
421 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
Interface Residues: 72, 74, 76, 77, 80, 81, 153, 306, 308, 310
3D-footprint Homologues: 6fzs_A, 5od6_A, 6h3r_A, 5nm9_A, 8k4l_B, 5mey_A, 1y8z_A, 2jej_A, 3qz7_A, 6l84_A, 4qwd_A, 2ago_A, 3pr5_B, 6vgm_D, 4tqr_A, 2agp_B, 1jx4_A, 2agq_A, 4qwc_D
Binding Motifs: UN0263.1 ttyCTTATCTctth
Binding Sites: UN0263.1.1
UN0263.1.10
UN0263.1.11
UN0263.1.12
UN0263.1.13
UN0263.1.14
UN0263.1.15
UN0263.1.16
UN0263.1.17
UN0263.1.18
UN0263.1.19
UN0263.1.2
UN0263.1.20
UN0263.1.3
UN0263.1.4
UN0263.1.5
UN0263.1.6
UN0263.1.7
UN0263.1.8
UN0263.1.9
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.