Transcription Factor

Accessions: 6ycq_A (3D-footprint 20231221)
Names: ARFA_ARATH, Auxin response factor 1
Organisms: Arabidopsis thaliana
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q8L7G0
Length: 347
Pfam Domains: 116-217 B3 DNA binding domain
242-324 Auxin response factor
Sequence:
(in bold interface residues)
1 GKPGGVLSDALCRELWHACAGPLVTLPREGERVYYFPEGHMEQLEASMHQGLEQQMPSFN 60
61 LPSKILCKVINIQRRAEPETDEVYAQITLLPELDQSEPTSPDAPVQEPEKCTVHSFCKTL 120
121 TASDTSTHGGFSVLRRHADDCLPPLDMSQQPPWQELVATDLHNSEWHFRHIFRGQPRRHL 180
181 LTTGWSVFVSSKKLVAGDAFIFLRGENEELRVGVRRHMRQQTNIPSSVISSHSMHIGVLA 240
241 TAAHAITTGTIFSVFYKPRTSRSEFIVSVNRYLEAKTQKLSVGMRFKMRFEGEEAPEKRF 300
301 SGTIVGVQENKSSVWHDSEWRSLKVQWDEPSSVFRPERVSPWELEPL
Interface Residues: 123, 128, 129, 130, 132, 173, 175, 176, 178
3D-footprint Homologues: 6ycq_A, 7et6_A, 6sdg_B
Binding Motifs: 6ycq_A TTGtCGgC
6ycq_AB TGTCGGtnnnnnGCCGACAA
Binding Sites: 6ycq_C
6ycq_D
Publications: Freire-Rios A, Tanaka K, Crespo I, van der Wijk E, Sizentsova Y, Levitsky V, Lindhoud S, Fontana M, Hohlbein J, Boer DR, Mironova V, Weijers D. Architecture of DNA elements mediating ARF transcription factor binding and auxin-responsive gene expression in Arabidopsis. Proc Natl Acad Sci U S A 117:24557-24566 (2020). [Pubmed]
Related annotations: PaperBLAST

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