Transcription Factor

						

			
Accessions: 1ttu_A (3D-footprint 20231221)

			
Names: lin-12 And Glp-1 transcriptional regulator, Q8MXE7_CAEEL
Organisms: Caenorhabditis elegans
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q8MXE7
Length: 435
Pfam Domains:    23-155 LAG1, DNA binding
  159-311 Beta-trefoil DNA-binding domain
  352-433 IPT/TIG domain
Sequence: 
(in bold interface residues)		   1 VQSLTSDRMIDFLSNKEKYECVISIFHAKVAQKSYGNEKRFFCPPPCIYLIGQGWKLKKD   60
  61 RVAQLYKTEQQATELVAYIGIGSDTSERQQLDFPNIYDYCAAKTLYISDSDKRKYFDLNA  120
 121 QFFYGCGMEIGGFVSQRIKVISKPSKKKQSMKNTDCKYLCIASGTKVALFNRLRSQTVST  180
 181 RYLHVEGNAFHASSTKWGAFTIHLFDDERGLQETDNFAVRDGFVYYGSVVKLVDSVTGIA  240
 241 LPRLRIRKVDKQQVILDASCSEEPVSQLHKCAFQMIDNELVYLCLSHDKIIQHQATAINE  300
 301 HRHQINDGAAWTIISTDKAEYRFFEAMGQVANPISPCPVVGSLEVDGHGEASRVELHGRD  360
 361 FKPNLKVWFGATPVETTFRSEESLHCSIPPVSQVRNEQTHWMFTNRTTGDVEVPISLVRD  420
 421 DGVVYSSGLTFSYKS
Interface Residues: 35, 38, 40, 142, 143, 146, 174, 175, 176
3D-footprint Homologues: 5e24_E, 3brd_A, 3iag_C
Binding Motifs: 1ttu_A tGngA
Binding Sites: 1ttu_B
1ttu_C
			
Publications: Kovall R.A, Hendrickson W.A. Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA. The EMBO journal 23:3441-51 (2004). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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