Transcription Factor
Accessions: | 1ttu_A (3D-footprint 20231221) |
Names: | lin-12 And Glp-1 transcriptional regulator, Q8MXE7_CAEEL |
Organisms: | Caenorhabditis elegans |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | Q8MXE7 |
Length: | 435 |
Pfam Domains: | 23-155 LAG1, DNA binding 159-311 Beta-trefoil DNA-binding domain 352-433 IPT/TIG domain |
Sequence: (in bold interface residues) | 1 VQSLTSDRMIDFLSNKEKYECVISIFHAKVAQKSYGNEKRFFCPPPCIYLIGQGWKLKKD 60 61 RVAQLYKTEQQATELVAYIGIGSDTSERQQLDFPNIYDYCAAKTLYISDSDKRKYFDLNA 120 121 QFFYGCGMEIGGFVSQRIKVISKPSKKKQSMKNTDCKYLCIASGTKVALFNRLRSQTVST 180 181 RYLHVEGNAFHASSTKWGAFTIHLFDDERGLQETDNFAVRDGFVYYGSVVKLVDSVTGIA 240 241 LPRLRIRKVDKQQVILDASCSEEPVSQLHKCAFQMIDNELVYLCLSHDKIIQHQATAINE 300 301 HRHQINDGAAWTIISTDKAEYRFFEAMGQVANPISPCPVVGSLEVDGHGEASRVELHGRD 360 361 FKPNLKVWFGATPVETTFRSEESLHCSIPPVSQVRNEQTHWMFTNRTTGDVEVPISLVRD 420 421 DGVVYSSGLTFSYKS |
Interface Residues: | 35, 38, 40, 142, 143, 146, 174, 175, 176 |
3D-footprint Homologues: | 3iag_C, 5e24_E, 3brd_A |
Binding Motifs: | 1ttu_A tGngA |
Binding Sites: | 1ttu_B 1ttu_C |
Publications: | Kovall R.A, Hendrickson W.A. Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA. The EMBO journal 23:3441-51 (2004). [Pubmed] |
Related annotations: | PaperBLAST |
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