Transcription Factor
Accessions: | 5d8l_F (3D-footprint 20231221) |
Names: | Heat shock factor protein 2, Heat shock transcription factor 2, HSF 2, HSF2_HUMAN, HSTF 2 |
Organisms: | Homo sapiens |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | Q03933 |
Length: | 98 |
Pfam Domains: | 4-97 HSF-type DNA-binding |
Sequence: (in bold interface residues) | 1 HMPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQL 60 61 NMYGFRKVVHIDDGPVEFQHPYFKQGQDDLLENIKRKV |
Interface Residues: | 6, 8, 9, 11, 46, 47, 49, 50, 55, 57, 58, 59, 61, 62, 96 |
3D-footprint Homologues: | 5x2h_A, 5hdn_C, 3hts_B, 5d5v_B, 5d5w_B, 7dci_A |
Binding Motifs: | 5d8l_DF AGAaAsnntTCT 5d8l_F tAGAa |
Binding Sites: | 5d8l_E 5d8l_G |
Publications: | Jaeger AM, Pemble CW 4th, Sistonen L, Thiele DJ. Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors. Nat Struct Mol Biol 23:147-54 (2016). [Pubmed] |
Related annotations: | PaperBLAST |
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