Transcription Factor
| Accessions: | Q6P3V2 (JASPAR 2024) |
| Names: | Z585A_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q6P3V2 |
| Length: | 769 |
| Pfam Domains: | 27-67 KRAB box 145-168 Zinc-finger double domain 176-195 Zinc-finger double domain 186-208 C2H2-type zinc finger 186-199 C2H2-type zinc finger 186-208 Zinc finger, C2H2 type 201-225 Zinc-finger double domain 213-225 C2H2-type zinc finger 214-236 Zinc finger, C2H2 type 214-236 C2H2-type zinc finger 228-253 Zinc-finger double domain 242-264 Zinc finger, C2H2 type 242-264 C2H2-type zinc finger 242-251 C2H2-type zinc finger 257-279 Zinc-finger double domain 285-307 Zinc-finger double domain 297-320 C2H2-type zinc finger 298-320 Zinc finger, C2H2 type 298-320 C2H2-type zinc finger 313-337 Zinc-finger double domain 328-348 C2H2-type zinc finger 355-376 C2H2-type zinc finger 355-374 C2H2-type zinc finger 356-376 Zinc finger, C2H2 type 371-393 Zinc-finger double domain 381-402 C2H2-type zinc finger 382-404 Zinc finger, C2H2 type 382-404 C2H2-type zinc finger 396-419 Zinc-finger double domain 410-432 Zinc finger, C2H2 type 425-449 Zinc-finger double domain 437-458 C2H2-type zinc finger 438-460 Zinc finger, C2H2 type 438-460 C2H2-type zinc finger 456-477 Zinc-finger double domain 466-488 Zinc finger, C2H2 type 466-488 C2H2-type zinc finger 468-488 C2H2-type zinc finger 480-505 Zinc-finger double domain 494-516 Zinc finger, C2H2 type 494-516 C2H2-type zinc finger 494-514 C2H2-type zinc finger 509-533 Zinc-finger double domain 521-531 C2H2-type zinc finger 522-544 Zinc finger, C2H2 type 522-544 C2H2-type zinc finger 536-560 Zinc-finger double domain 550-572 Zinc finger, C2H2 type 550-570 C2H2-type zinc finger 567-587 Zinc-finger double domain 578-600 C2H2-type zinc finger 578-600 Zinc finger, C2H2 type 578-598 C2H2-type zinc finger 595-617 Zinc-finger double domain 605-624 C2H2-type zinc finger 606-625 C2H2-type zinc finger 606-625 Zinc finger, C2H2 type 623-644 Zinc-finger double domain 634-656 C2H2-type zinc finger 634-656 Zinc finger, C2H2 type 634-656 C2H2-type zinc finger 648-672 Zinc-finger double domain 662-680 C2H2-type zinc finger 662-682 C2H2-type zinc finger 662-684 Zinc finger, C2H2 type 679-700 Zinc-finger double domain 689-708 C2H2-type zinc finger 690-712 C2H2-type zinc finger 690-712 Zinc finger, C2H2 type 705-728 Zinc-finger double domain 718-740 Zinc finger, C2H2 type 718-740 C2H2-type zinc finger 718-740 C2H2-type zinc finger 732-756 Zinc-finger double domain 745-756 C2H2-type zinc finger 746-768 C2H2-type zinc finger 746-768 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MPANWTSPQKSSALAPEDHGSSYEGSVSFRDVAIDFSREEWRHLDPSQRNLYRDVMLETY 60 61 SHLLSVGYQVPEAEVVMLEQGKEPWALQGERPRQSCPGEKLWDHNQCRKILSYKQVSSQP 120 121 QKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGKAFVQKPEFIIHQKTH 180 181 MREKPFKCNECGKSFFQVSSLFRHQRIHTGEKLYECSQCGKGFSYNSDLSIHEKIHTGER 240 241 HHECTDCGKAFTQKSTLKMHQKIHTGERSYICIECGQAFIQKTHLIAHRRIHTGEKPYEC 300 301 SNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLVTHKKVQSREKSSICTECG 360 361 KAFTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVHQRIHTGEKSYICMKCGLAFI 420 421 QKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGKAFTNRSN 480 481 LITHQKTHTGEKSYICSKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKAFTQKSHLNIH 540 541 QKIHTGERQYECHECGKAFNQKSILIVHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIH 600 601 TGEKPYECSDCGKSFTSKSQLLVHQPVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEK 660 661 PYICSECGKTFRQKSELITHHRIHTGEKPYECSDCGKSFTKKSQLQVHQRIHTGEKPYVC 720 721 AECGKAFTDRSNLNKHQTTHTGDKPYKCGICGKGFVQKSVFSVHQSSHA |
| Interface Residues: | 337, 340, 343, 347, 365, 367, 368, 371, 393, 394, 395, 396, 399, 421, 424, 448, 449, 450, 451, 452, 455, 476, 477, 478, 479, 480, 482, 483, 487, 505, 506, 507, 508, 510, 511, 515, 522, 533, 534, 535, 536, 539, 560, 561, 562, 563, 564, 567, 588, 589, 590, 591, 592, 595, 616, 617, 618, 619, 620, 623, 627, 645, 646, 647, 648, 650, 651, 657, 671, 672, 673, 674, 675, 676, 678, 679, 680, 681, 682, 683, 685, 700, 701, 702, 703, 704, 705, 706, 707, 708, 728, 729, 730, 731, 732, 734, 735, 757, 758, 759, 760, 763 |
| 3D-footprint Homologues: | 8ssu_A, 5und_A, 5k5i_A, 3uk3_C, 7w1m_H, 5k5l_F, 7eyi_G, 7y3m_I, 2drp_D, 8ssq_A, 5v3j_F, 8gn3_A, 6u9q_A, 2lt7_A, 2kmk_A, 2gli_A, 1ubd_C, 2i13_A, 5yel_A, 6jnm_A, 1tf6_A, 5kkq_D, 5kl3_A, 6ml4_A, 4x9j_A, 5ei9_F, 1mey_C, 6wmi_A, 7ysf_A, 7n5w_A, 1g2f_F, 1llm_D, 6blw_A, 2wbs_A, 7txc_E, 1f2i_J, 4m9v_C, 8h9h_G, 6e94_A, 6a57_A, 2jpa_A, 1tf3_A, 8cuc_F, 7y3l_A, 5yj3_D |
| Binding Motifs: | UN0637.1 rawAGAGAACAga UN0637.2 wAGAGAACAg |
| Binding Sites: | UN0637.1.1 / UN0637.1.3 UN0637.1.10 / UN0637.1.18 UN0637.1.11 UN0637.1.12 UN0637.1.13 UN0637.1.14 UN0637.1.15 UN0637.1.16 UN0637.1.17 UN0637.1.18 UN0637.1.19 UN0637.1.2 / UN0637.1.4 UN0637.1.20 UN0637.1.3 / UN0637.1.6 UN0637.1.4 / UN0637.1.7 UN0637.1.5 / UN0637.1.8 UN0637.1.12 / UN0637.1.6 UN0637.1.13 / UN0637.1.7 UN0637.1.16 / UN0637.1.8 UN0637.1.17 / UN0637.1.9 UN0637.1.1 UN0637.1.10 UN0637.1.11 UN0637.1.14 UN0637.1.15 UN0637.1.19 UN0637.1.2 UN0637.1.20 UN0637.1.5 UN0637.1.9 UN0637.2.1 UN0637.2.10 UN0637.2.11 / UN0637.2.3 / UN0637.2.8 UN0637.2.12 / UN0637.2.2 UN0637.2.13 UN0637.2.14 UN0637.2.15 UN0637.2.16 UN0637.2.17 / UN0637.2.18 / UN0637.2.7 UN0637.2.19 UN0637.2.20 UN0637.2.4 UN0637.2.5 UN0637.2.6 UN0637.2.9 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.