Transcription Factor

Accessions: T016875_1.02 (CISBP 1.02)
Names: l(1)sc, T016875_1.02;
Organisms: Drosophila melanogaster
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:B1H, family:bHLH
Length: 257
Pfam Domains: 87-146 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 MTSICSSKFQQQHYQLTNSNIFLLQHQHHHQTQQHQLIAPKIPLGTSQLQNMQQSQQSNV 60
61 GPMLSSQKKKFNYNNMPYGEQLPSVARRNARERNRVKQVNNGFVNLRQHLPQTVVNSLSN 120
121 GGRGSSKKLSKVDTLRIAVEYIRGLQDMLDDGTASSTRHIYNSADESSNDGSSYNDYNDS 180
181 LDSSQQFLTGATQSAQSHSYHSASPTPSYSGSEISGGGYIKQELQEQDLKFDSFDSFSDE 240
241 QPDDEELLDYISSWQEQ
Interface Residues: 88, 89, 91, 92, 95, 96
3D-footprint Homologues: 2ypa_A, 7z5k_B, 8osb_B, 2ql2_D
Binding Motifs: M5064_1.02 GCAGGTG
Related annotations: PaperBLAST

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