Transcription Factor

						

			
Accessions: 2i9t_A (3D-footprint 20231221)

			
Names: Nuclear factor NF-kappa-B p65 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, TF65_MOUSE, Transcription factor p65
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q04207
Length: 275
Pfam Domains:     5-170 Rel homology domain (RHD)
Sequence: 
(in bold interface residues)		   1 HAPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISL   60
  61 VTKDPPHRPHPHELVGKDCRDGYYEADLCPDRSIHSFQNLGIQCVKKRDLEQAISQRIQT  120
 121 NNNPFHVPIEEQRGDYDLNAVRLCFQVTVRDPAGRPLLLTPVLSHPIFDNRAPNTAELKI  180
 181 CRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPP  240
 241 YADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPD
Interface Residues: 17, 19, 20, 22, 23, 25, 26, 27, 119, 171, 173, 202, 230
3D-footprint Homologues: 1gji_A, 2ram_A, 1imh_C, 7cli_B, 1a3q_A, 1nfk_A, 1a66_A, 2o61_A
Binding Motifs: 2i9t_AB GGaanTtCCC
			
Publications: Escalante C.R, Shen L, Thanos D, Aggarwal A.K. Structure of NF-kappaB p50/p65 heterodimer bound to the PRDII DNA element from the interferon-beta promoter. Structure (London, England : 1993) 10:383-91 (2002). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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