Transcription Factor

Accessions: UP00062A (UniPROBE 20160601)
Names: AA682046, Sox-4, Sox4, SRY-box containing gene 4, Transcription factor SOX-4
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q06945
Description: SRY-box containing gene 4: Mus musculus BAC Clone 262c6 RPCI-23, complete sequence
Length: 101
Pfam Domains: 17-85 HMG (high mobility group) box
18-75 Domain of unknown function (DUF1898)
Sequence:
(in bold interface residues)
1 GGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKD 60
61 SDKIPFIQEAERLRLKHMADYPDYKYRPRKKVKSGNAGAGS
Interface Residues: 19, 22, 24, 25, 28, 32, 43, 44, 45, 48, 86, 90
3D-footprint Homologues: 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 4s2q_D, 1qrv_A, 3tmm_A, 4y60_C, 2gzk_A, 1j5n_A, 6jrp_D, 2lef_A, 1hry_A, 3tq6_B, 1ckt_A
Binding Motifs: UP00062A_1 akdarAACAAAGracww
UP00062A_2 grwarAATTGTtasrra
Binding Sites: AAACAAAG
AACAAAAG
AACAAAGA
AACAAAGC
AACAATAA
AACAATAG
AACAATGG
AATTGTTC
ACAAAGAA
ACAAAGAG
ACAAAGGA
ACAACAAT
ACAATAGA
AGAACAAT
AGACAAAG
AGACAATA
CTTTGTTA
CTTTGTTC
GAACAATA
GACAAAGA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.