Transcription Factor

Accessions: UP00576A (UniPROBE 20160601)
Names: NTL6, transcription factor NTL6
Organisms: Arabidopsis thaliana
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Description: transcription factor NTL6: Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (PubMed:20156199, PubMed:19947982). Transcriptional activator involved in response to cold stress. Mediates induction of pathogenesis-related (PR) genes independently of salicylic signaling in response to cold. Binds directly to the PR gene promoters and enhances plant
Length: 168
Pfam Domains: 13-141 No apical meristem (NAM) protein
Sequence:
(in bold interface residues)
1 MNQNLHVLSMDSLPVGLRFRPTDEELIRYYLRRKINGHDDDVKAIREIDICKWEPWDLPD 60
61 FSVIKTKDSEWLYFCPLDRKYPSGSRQNRATVAGYWKATGKDRKIKSGKTNIIGVKRTLV 120
121 FHAGRAPRGTRTNWIIHEYRATEDDLSGTNPGQSPFVICKLFKKEELV
Interface Residues: 81, 86, 88, 97, 99, 101, 122, 126, 127, 128, 131
3D-footprint Homologues: 7xp3_B, 3swp_A
Binding Motifs: UP00576A_1 stACACGCAAcC
UP00576A_2 gggTAAGkAAwht
Binding Sites: CACGGCAC
TTACGCAA
ACACGCAA
ACACGCCA
ACACGGAA
ACACGGCA
ACACGTAA
ACACGTCA
ACACGTTA
ACGCAACC
ACGCAACT
ACGCAATC
ATTGCGTA
ATTGCGTG
CACGCAAC
CACGTAAC
GCACGCAA
GTACGCAA
GTTGCGTA
TCACGCAA
Publications: Lindemose S, Jensen MK, Van de Velde J, O'Shea C, Heyndrickx KS, Workman CT, Vandepoele K, Skriver K, De Masi F. A DNA-binding-site landscape and regulatory network analysis for NAC transcription factors in Arabidopsis thaliana. Nucleic Acids Res 42:7681-93 (2014). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.