Transcription Factor
Accessions: | 2fo1_A (3D-footprint 20231221) |
Names: | Lin-12 and glp-1 phenotype protein 1, isoform b, Q8MXE7_CAEEL |
Organisms: | Caenorhabditis elegans |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Length: | 439 |
Pfam Domains: | 23-162 LAG1, DNA binding 166-312 Beta-trefoil DNA-binding domain 353-434 IPT/TIG domain |
Sequence: (in bold interface residues) | 1 VQSLTSDRMIDFLSNKEKYECVISIFHAKVAQKSYGNEKRFFCPPPCIYLIGQGWKLKKD 60 61 RVAQLYKTLKASAIHEQQATELVAYIGIGSDTSERQQLDFSTGKVRHPNIYDYCAAKTLY 120 121 ISDSDKRKYFDLNAQFFYGCGMEIGGFVSQRIKVISKPSKKDCKYLCIASGTKVALFNRL 180 181 RSQTVSTRYLHVEGNAFHASSTKWGAFTIHLFDDEDNFAVRDGFVYYGSVVKLVDSVTGI 240 241 ALPRLRIRKVDKQQVILDASCSEEPVSQLHKCAFQMIDNELVYLCLSHDKIIQHQATAIN 300 301 EHRHQINDGAAWTIISTDKAEYRFFEAMGQVANPISPCPVVGSLEVDGHGEASRVELHGR 360 361 DFKPNLKVWFGATPVETTFRSEESLHCSIPPVSQVRNEQTHWMFTNRTTGDVEVPISLVR 420 421 DDGVVYSSGLTFSYKSLER |
Interface Residues: | 35, 38, 40, 156, 157, 160, 181, 182, 183 |
3D-footprint Homologues: | 3brd_A, 3iag_C, 5e24_E |
Binding Motifs: | 2fo1_A TTCnCAC |
Binding Sites: | 2fo1_B 2fo1_C |
Publications: | Wilson J.J, Kovall R.A. Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA. Cell 124:985-96 (2006). [Pubmed] |
Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.