Transcription Factor

						

			
Accessions: 2fo1_A (3D-footprint 20231221)

			
Names: Lin-12 and glp-1 phenotype protein 1, isoform b, Q8MXE7_CAEEL
Organisms: Caenorhabditis elegans
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 439
Pfam Domains:    23-162 LAG1, DNA binding
  166-312 Beta-trefoil DNA-binding domain
  353-434 IPT/TIG domain
Sequence: 
(in bold interface residues)		   1 VQSLTSDRMIDFLSNKEKYECVISIFHAKVAQKSYGNEKRFFCPPPCIYLIGQGWKLKKD   60
  61 RVAQLYKTLKASAIHEQQATELVAYIGIGSDTSERQQLDFSTGKVRHPNIYDYCAAKTLY  120
 121 ISDSDKRKYFDLNAQFFYGCGMEIGGFVSQRIKVISKPSKKDCKYLCIASGTKVALFNRL  180
 181 RSQTVSTRYLHVEGNAFHASSTKWGAFTIHLFDDEDNFAVRDGFVYYGSVVKLVDSVTGI  240
 241 ALPRLRIRKVDKQQVILDASCSEEPVSQLHKCAFQMIDNELVYLCLSHDKIIQHQATAIN  300
 301 EHRHQINDGAAWTIISTDKAEYRFFEAMGQVANPISPCPVVGSLEVDGHGEASRVELHGR  360
 361 DFKPNLKVWFGATPVETTFRSEESLHCSIPPVSQVRNEQTHWMFTNRTTGDVEVPISLVR  420
 421 DDGVVYSSGLTFSYKSLER
Interface Residues: 35, 38, 40, 156, 157, 160, 181, 182, 183
3D-footprint Homologues: 3brd_A, 3iag_C, 5e24_E
Binding Motifs: 2fo1_A TTCnCAC
Binding Sites: 2fo1_B
2fo1_C
			
Publications: Wilson J.J, Kovall R.A. Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA. Cell 124:985-96 (2006). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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