Transcription Factor
| Accessions: | 3r8f_A (3D-footprint 20231221), 3r8f_B (3D-footprint 20231221), 3r8f_C (3D-footprint 20231221), 3r8f_D (3D-footprint 20231221) |
| Names: | Chromosomal replication initiator protein dnaA, DNAA_AQUAE |
| Organisms: | Aquifex aeolicus, strain VF5 |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | O66659 |
| Length: | 319 |
| Pfam Domains: | 3-210 Bacterial dnaA protein 39-143 IstB-like ATP binding protein 40-159 ATPase family associated with various cellular activities (AAA) 231-296 Bacterial dnaA protein helix-turn-helix |
| Sequence: (in bold interface residues) | 1 DFLNPKYTLENFIVGEGNRLAYEVVKEALENLGSLYNPIFIYGSVGTGKTHLLQAAGNEA 60 61 KKRGYRVIYSSADDFAQAMVEHLKKGTINEFRNMYKSVDLLLLDDVQFLSGKERTQIEFF 120 121 HIFNTLYLLEKQIILASDRHPQKLDGVSDRLVSRFEGGILVEIELDNKTRFKIIKEKLKE 180 181 FNLELRKEVIDYLLENTKNVREIEGKIKLIKLKGFEGLERKERKERDKLMQIVEFVANYY 240 241 AVKVEDILSDKNKRTSEARKIAMYLCRKVCSASLIEIARAFKRKDHTTVIHAIRSVEEEK 300 301 RKFKHLVGFLEKQAFDKIC |
| Interface Residues: | 80, 83, 84, 251, 275, 285, 286, 287, 290, 291 |
| 3D-footprint Homologues: | 6qem_L, 3r8f_C, 3pvv_B |
| Binding Motifs: | 3r8f_ABCD AnnAnnanna |
| Binding Sites: | 3r8f_E |
| Publications: | Duderstadt K.E, Chuang K, Berger J.M. DNA stretching by bacterial initiators promotes replication origin opening. Nature 478:209-13 (2011). [Pubmed] |
| Related annotations: | PaperBLAST |
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