Transcription Factor
| Accessions: | 1k6o_C (3D-footprint 20231221) |
| Names: | Serum response factor, SRF_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P11831 |
| Length: | 84 |
| Pfam Domains: | 12-62 SRF-type transcription factor (DNA-binding and dimerisation domain) |
| Sequence: (in bold interface residues) | 1 KKTRGRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVLLLVASETGHVYTF 60 61 ATRKLQPMITSETGKALIQTCLNS |
| Interface Residues: | 3, 6, 7, 18, 21, 22, 26 |
| 3D-footprint Homologues: | 1hbx_A, 1n6j_A, 1c7u_A, 7x1n_C, 1mnm_A |
| Binding Motifs: | 1k6o_ABC AGGATnTCCATATTAGGA |
| Binding Sites: | 1k6o_D 1k6o_E |
| Publications: | Mo Y, Ho W, Johnston K, Marmorstein R. Crystal structure of a ternary SAP-1/SRF/c-fos SRE DNA complex. Journal of molecular biology 314:495-506 (2001). [Pubmed] |
| Related annotations: | PaperBLAST |
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