Transcription Factor

Accessions: 1if1_A (3D-footprint 20231221)
Names: INTERFERON REGULATORY FACTOR 1, IRF-1, IRF1_MOUSE
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P15314
Length: 105
Pfam Domains: 1-105 Interferon regulatory factor transcription factor
Sequence:
(in bold interface residues)
1 RMRPWLEMQINSNQIPGLIWINKEEMIFQIPWKHAAKHGWDINKDACLFRSWAIHTGRYK 60
61 AGEKEPDPKTWKANFRCAMNSLPDIEEVKDQSRNKGSSAVRVYRM
Interface Residues: 34, 36, 45, 69, 73, 74, 76, 77, 80, 81, 84
3D-footprint Homologues: 2pi0_B, 1if1_B, 2o61_A, 5xh6_A, 2irf_L, 7oot_B
Binding Motifs: 1if1_AB TGGAnnTACtTACA
Publications: ESCALANTE C.R., YIE J., THANOS D., AGGARWAL A.K. Structure of IRF-1 with bound DNA reveals determinants of interferon regulation.. Nature 391:103-106 (1998). [Pubmed]
Related annotations: PaperBLAST

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