Transcription Factor

Accessions: T049165_1.02 (CISBP 1.02)
Names: Egr3, T049165_1.02;
Organisms: Mus musculus
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:C2H2 ZF
Length: 387
Pfam Domains: 87-156 Domain of unknown function (DUF3446)
275-299 C2H2-type zinc finger
275-299 Zinc finger, C2H2 type
292-315 Zinc-finger double domain
305-327 C2H2-type zinc finger
305-327 Zinc finger, C2H2 type
319-343 Zinc-finger double domain
333-353 C2H2-type zinc finger
333-355 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MTGKLAEKLPVTMSSLLNQLPDNLYPEEIPSALNLFSGSSDSVAHYNQMATENVMDIGLT 60
61 NEKPNPELSYSSSFQPAPGNKTVTYLGKFAFDSPSNWCQDNIISLMSAGILGVPPASGAL 120
121 STQTSTASMVQPPQGDVEAMYPALPPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSAK 180
181 PALDSNLFPMIPDYNLYHHPNDMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIH 240
241 PGFGSLPQPPLTLKPIRPRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHT 300
301 GHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKE 360
361 KKSEKGGAPSASSAPTVSLAPVVTTCA
Interface Residues: 257, 261, 264, 267, 270, 286, 287, 288, 289, 290, 291, 293, 294, 315, 316, 317, 318, 319, 321, 322, 323, 343, 344, 345, 346, 347, 348, 349, 350, 351, 354
3D-footprint Homologues: 8ssu_A, 5kkq_D, 8ssq_A, 7w1m_H, 5ei9_F, 5v3j_F, 6blw_A, 8gn3_A, 1tf3_A, 7n5w_A, 6jnm_A, 2kmk_A, 6u9q_A, 4x9j_A, 2gli_A, 1f2i_J, 5kl3_A, 1tf6_A, 2jpa_A, 1g2f_F, 7ysf_A, 6ml4_A, 1ubd_C, 8h9h_G, 6e94_A, 2lt7_A, 6a57_A, 8cuc_F, 7y3l_A, 3uk3_C, 1llm_D, 5yel_A, 2drp_D, 2wbs_A, 7txc_E, 5k5i_A, 4m9v_C, 7y3m_I, 5yj3_D
Binding Motifs: M0414_1.02 rcGkGGGcgk
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.