Transcription Factor
| Accessions: | Q01094 (JASPAR 2024) |
| Names: | E2F-1, E2F1_HUMAN, PBR3, pRB-binding protein E2F-1, RBAP-1, RBBP-3, Retinoblastoma-associated protein 1, Retinoblastoma-binding protein 3, Transcription factor E2F1 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q01094 |
| Length: | |
| Binding Motifs: | MA0024.3 tttGGCGCCaaa MA0024.2 sgsGCGSSArv MA0024.1 TTTsGCGC |
| Binding Sites: | MA0024.1.2 / MA0024.1.3 / MA0024.1.4 MA0024.1.5 / MA0024.1.6 / MA0024.1.7 MA0024.1.8 MA0024.1.10 MA0024.1.9 MA0024.1.1 MA0024.2.1 MA0024.2.10 / MA0024.2.13 MA0024.2.11 MA0024.2.12 MA0024.2.14 MA0024.2.15 MA0024.2.16 MA0024.2.17 MA0024.2.18 MA0024.2.19 MA0024.2.2 MA0024.2.20 MA0024.2.3 MA0024.2.4 MA0024.2.5 MA0024.2.6 MA0024.2.7 MA0024.2.8 MA0024.2.9 |
| Publications: | Nevins R. E2F: A link between the Rb tumor suppressor protein and viral oncoproteins. Science 258:424-429 (1992). [Pubmed] Tao Y., Kassatly R. F., Cress W. D., Horowitz J. M. Subunit composition determines E2F DNA-binding site specificity. Mol. Cell. Biol. 17:6994-7007 (1997). [Pubmed] Xu X., Bieda M., Jin V. X., Rabinovich A., Oberley M. J., Green R., Farnham P. J. A comprehensive ChIP-chip analysis of E2F1, E2F4, and E2F6 in normal and tumor cells reveals interchangeable roles of E2F family members.. Genome Res. 17:1550-1561 (2007). [Pubmed] |
| Related annotations: | PaperBLAST |
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