Transcription Factor

Accessions: Q06546 (JASPAR 2024)
Names: GA-binding protein alpha chain, GABP subunit alpha, GABPA_HUMAN, Nuclear respiratory factor 2 subunit alpha, Transcription factor E4TF1-60
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q06546
Length:
Binding Motifs: MA0062.1 ACCGGAAGws
MA0062.3 yycACTTCCTGtyy
MA0062.4 cACTTCCTGt
Binding Sites: MA0062.1.1
MA0062.1.2 / MA0062.1.3
MA0062.1.7
MA0062.1.6
MA0062.1.5
MA0062.1.4
MA0062.3.1
MA0062.3.10 / MA0062.3.6
MA0062.3.11 / MA0062.3.7
MA0062.3.12
MA0062.3.13 / MA0062.3.8
MA0062.3.14 / MA0062.3.9
MA0062.3.10 / MA0062.3.15
MA0062.3.11 / MA0062.3.16
MA0062.3.12 / MA0062.3.17
MA0062.3.18
MA0062.3.19
MA0062.3.2
MA0062.3.20
MA0062.3.3
MA0062.3.4
MA0062.3.5
MA0062.3.6
MA0062.3.4 / MA0062.3.7
MA0062.3.5 / MA0062.3.8
MA0062.3.9
MA0062.3.1
MA0062.3.13
MA0062.3.14
MA0062.3.15
MA0062.3.16
MA0062.3.17
MA0062.3.18
MA0062.3.19
MA0062.3.20
MA0062.4.1
MA0062.4.10
MA0062.4.11 / MA0062.4.4
MA0062.4.12
MA0062.4.13
MA0062.4.14
MA0062.4.15
MA0062.4.16
MA0062.4.17
MA0062.4.18
MA0062.4.19
MA0062.4.2
MA0062.4.20
MA0062.4.3 / MA0062.4.7
MA0062.4.5
MA0062.4.6
MA0062.4.8
MA0062.4.9
Publications: Virbasius J. V., Virbasius C.-M. A., Scarpulla R. C. Identity of GABP with NRF-2, a multisubunit activator of cytochrome oxidase expression, reveals a cellular role for an Ets domain activator of viral promoters. Genes Dev. 7:380-392 (1993). [Pubmed]

Batchelor A.H, Piper D.E, de la Brousse F.C, McKnight S.L, Wolberger C. The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA. Science (New York, N.Y.) 279:1037-41 (1998). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.