Transcription Factor

Accessions: UP00522A (UniPROBE 20160601)
Names: FOXN4
Organisms: Homo sapiens
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 127
Pfam Domains: 16-106 Fork head domain
Sequence:
(in bold interface residues)
1 GAMHASQEPHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGW 60
61 KNSVRHNLSLNKCFEKVETKSSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSM 120
121 ANPEELD
Interface Residues: 13, 59, 61, 62, 63, 65, 66, 67, 69, 70, 80, 87
3D-footprint Homologues: 7yzg_A, 7yz7_A, 7vox_H, 2hdc_A, 7tdx_A, 3l2c_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7tdw_A, 3g73_A, 6el8_A, 3qrf_G
Binding Motifs: UP00522A_1 sstrkwrATrGCGTCtytwygw
UP00522A_2 aatcgarrsGACGCyAyawykms
UP00522A_3 dgamcckvCGCGTCmmvyryck
UP00522A_4 gswAgmCgwmCGCGTCykkmmt
Binding Sites: GACGCGTC
ACCGCGTC
ACGCGTCC
AGACGCCA
AGACGCTA
AGGGACGC
ATAGCGTC
ATCGCGTC
ATGACGCG
ATGGCGTC
CCGCGTCC
CGACGCTA
CGCGTCCC
CGGCGTCC
GACGCTAA
GACGCTAC
GCGTCATA
GGACGCCA
GGACGCTA
TAGCGTCA
Publications: Nakagawa S, Gisselbrecht SS, Rogers JM, Hartl DL, Bulyk ML. DNA-binding specificity changes in the evolution of forkhead transcription factors. Proc Natl Acad Sci U S A 110:12349-54 (2013). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.