Transcription Factor

						

			
Accessions: 4ati_B (3D-footprint 20231221)

			
Names: MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR, MITF_MOUSE
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q08874
Length: 71
Pfam Domains:      3-55 Helix-loop-helix DNA-binding domain
Sequence: 
(in bold interface residues)		   1 RQKKDNHNLIERRRRFNINDRIKELGTLIPKSDPDMRWNKGTILKASVDYIRKLQREQQR   60
  61 AKDLENRQKKL
Interface Residues: 4, 7, 8, 10, 11, 14, 15, 38, 40
3D-footprint Homologues: 1a0a_B, 6g1l_A, 4h10_B, 7ssa_L, 5i50_B, 7d8t_A, 4zpk_A, 7xi3_A, 5nj8_D, 7f2f_B, 5eyo_A, 1am9_A, 5v0l_A, 4h10_A, 7rcu_E, 5gnj_I, 8osl_O, 8osl_P, 1an4_A, 2ypa_A, 7z5k_B, 2vs7_A
Binding Motifs: 4ati_B agCAca
4ati_AB TCATGTGCT
Binding Sites: 4ati_C
4ati_D
			
Publications: Pogenberg V, Ogmundsdóttir M.H, Bergsteinsdóttir K, Schepsky A, Phung B, Deineko V, Milewski M, Steingrímsson E, Wilmanns M. Restricted leucine zipper dimerization and specificity of DNA recognition of the melanocyte master regulator MITF. Genes & development 26:2647-58 (2012). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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