Transcription Factor

Accessions: T093324_1.02 (CISBP 1.02)
Names: MEIS1, T093324_1.02;
Organisms: Homo sapiens
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: family:Homeodomain
Length: 253
Pfam Domains: 131-185 Homeobox domain
146-185 Homeobox KN domain
Sequence:
(in bold interface residues)
1 MIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDDREGGSKSDSEDITRS 60
61 ANLTDQPSWNRDHDDTASTRSGGTPGPSSGGHTSHSGDNSSEQGDGLDNSVASPSTGDDD 120
121 DPDKDKKRHKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFI 180
181 NARRRIVQPMIDQSNRAVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGPMSGMGMNMGPP 240
241 CIRTFLDTLTTQQ
Interface Residues: 129, 131, 132, 173, 176, 177, 180, 181, 182, 183, 184, 185, 195, 209, 212
3D-footprint Homologues: 6fqp_B, 1puf_B, 8ik5_C, 7q3o_C, 1le8_A, 4j19_B, 8osb_E, 1k61_B, 4xrs_G, 6es3_K, 3rkq_B, 5hod_A, 2d5v_B, 1le8_B, 5zfz_A, 3cmy_A, 1fjl_B, 6fqq_E, 4xrm_B, 1mnm_C, 6a8r_A, 3lnq_A
Binding Motifs: M3562_1.02 yhrTGACAGrds
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.