Transcription Factor

						

			
Accessions: Q00056 (JASPAR 2024)

			
Names: Homeobox protein Hox-1.4, Homeobox protein Hox-1D, Homeobox protein Hox-A4, HXA4_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q00056
Length: 320
Pfam Domains:   216-272 Homeobox domain
Sequence: 
(in bold interface residues)		   1 MTMSSFLINSNYIEPKFPPFEEYAQHSGSGGADGGPGGGPGYQQPPAPPTQHLPLQQPQL   60
  61 PHAGGGREPTASYYAPRTAREPAYPAAALYPAHGAADTAYPYGYRGGASPGRPPQPEQPP  120
 121 AQAKGPAHGLHASHVLQPQLPPPLQPRAVPPAAPRRCEAAPATPGVPAGGSAPACPLLLA  180
 181 DKSPLGLKGKEPVVYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYL  240
 241 TRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAGPPGKAQTQ  300
 301 SPHLHPHPHPSTSTPVPSSI
Interface Residues: 170, 171, 172, 175, 176, 196, 199, 200, 203, 216, 217, 218, 219, 257, 258, 260, 261, 264, 265, 268, 269, 272
3D-footprint Homologues: 3d1n_M, 5zfz_A, 1puf_A, 1ig7_A, 3cmy_A, 1fjl_B, 6a8r_A, 2h1k_B, 3lnq_A, 2lkx_A, 1jgg_B, 6m3d_C, 1nk2_P, 1zq3_P, 7q3o_C, 6es3_K, 2ld5_A, 1b72_A, 5jlw_D, 4xrs_G, 2hdd_A, 3rkq_B, 2r5y_A, 1puf_B, 5flv_I, 2hos_A, 5zjt_E, 4cyc_A, 7psx_B, 3a01_E, 1le8_A, 7xrc_C, 1e3o_C, 2xsd_C, 1mnm_C, 1du0_A, 1k61_B, 5hod_A, 3l1p_A, 1o4x_A, 4qtr_D
Binding Motifs: MA1496.1 rYmATTAr
MA1496.2 rYmATTA
			
Publications: Wu K, Wolgemuth DJ. Protein product of the somatic-type transcript of the Hoxa-4 (Hox-1. 4) gene binds to homeobox consensus binding sites in its promoter and intron 52:449-62 (J). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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