Transcription Factor
| Accessions: | UP00186A (UniPROBE 20160601) |
| Names: | C530044H18Rik, Evi8, Homeobox protein Meis1, Meis1, myeloid ecotropic viral integration site 1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q60954 |
| Description: | myeloid ecotropic viral integration site 1 |
| Length: | 96 |
| Pfam Domains: | 18-73 Homeobox domain 34-73 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 SPSTGDDDDPDKDKKRHKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTI 60 61 LQVNNWFINARRRIVQPMIDQSNRAVSQGTPYNPDG |
| Interface Residues: | 17, 19, 20, 64, 65, 68, 69, 70, 72, 73 |
| 3D-footprint Homologues: | 6fqp_B, 1puf_B, 1le8_A, 7q3o_C, 1au7_A, 4j19_B, 1fjl_B, 4xrm_B, 1mnm_C, 5zfz_A, 3lnq_A, 1k61_B, 6fqq_E, 4xrs_G, 6a8r_A, 3rkq_B, 5flv_I, 2d5v_B, 6es3_K, 1le8_B, 8g87_X, 5hod_A, 3cmy_A |
| Binding Motifs: | UP00186A_1 wasbAsCTGTCAWwac |
| Binding Sites: | AACTGTCA AATGACAG ACATGTCA ACCTGTCA AGCTGTCA ATCTGTCA ATGACAGC ATGACAGG ATTGACAG CCTGTCAA CCTGTCAC CTGACAGC CTGTCAAA CTGTCAAC GCCTGTCA GCTGTCAA GCTGTCAC GGCTGTCA TCCTGTCA TGACAGCA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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