Transcription Factor

						

			
Accessions: UP00021A (UniPROBE 20160601)

			
Names: MGC70044, MGC7737, Zfp281, Zinc finger protein 281
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q99LI5
Description: Zinc finger protein 281: Mus musculus zinc finger protein 281, mRNA
Length: 137
Pfam Domains:     16-38 C2H2-type zinc finger
    16-38 Zinc finger, C2H2 type
    30-53 Zinc-finger double domain
    44-66 C2H2-type zinc finger
    44-66 Zinc finger, C2H2 type
    59-81 Zinc-finger double domain
    73-94 Zinc finger, C2H2 type
    74-94 C2H2-type zinc finger
   87-110 Zinc-finger double domain
  100-122 C2H2-type zinc finger
  100-122 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 VGEGEGAVLSPSQKPHICDHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQKYLLQ   60
  61 RHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTDRLLKHRR  120
 121 TCGEAIAKGAASAEPGS
Interface Residues: 12, 13, 26, 27, 28, 29, 30, 32, 33, 34, 35, 36, 37, 39, 44, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 65, 77, 80, 82, 83, 84, 85, 86, 88, 89, 111, 112, 113, 114, 115, 116, 117, 128, 130
3D-footprint Homologues: 1yuj_A, 7n5w_A, 5yel_A, 3uk3_C, 1tf3_A, 7w1m_H, 5k5l_F, 5v3j_F, 8gn3_A, 5kkq_D, 6u9q_A, 5ei9_F, 5k5i_A, 8ssq_A, 2gli_A, 1g2f_F, 8ssu_A, 1tf6_A, 6ml4_A, 8h9h_G, 4m9v_C, 7eyi_G, 2i13_A, 7y3m_I, 6e94_A, 7ysf_A, 6wmi_A, 2jpa_A, 1ubd_C, 2kmk_A, 6jnm_A, 7y3l_A, 6blw_A, 1mey_C, 5kl3_A, 5yj3_D, 5und_A, 4x9j_A, 6a57_A, 2lt7_A, 8cuc_F, 1llm_D, 2wbs_A, 7txc_E, 1f2i_J
Binding Motifs: UP00021A_1 tcmCCmyCCCCCmyc
UP00021A_2 akkwkaCCCCCAwtwwr
Binding Sites: AACCCCCA
AACCCCCC
AAGGGGGG
ACCCCCAC
ACCCCCCA
AGGGGGGG
ATGGGGGG
CACCCCCA
CACCCCCC
CCACCCCC
CCCCCACC
CCCCCCAA
CCCCCCAC
CCCCCCCA
CCCCCCCC
CCCCCCTC
CCTCCCCC
CTCCCCCC
GGGGGGGA
GGGGGGTA
			
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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