Transcription Factor

						

			
Accessions: ZSCAN4 (SMILE-seq 1.0)

			
Names: Zinc finger and SCAN domain-containing protein 4, Zinc finger protein 494, ZSCA4_HUMAN, ZSCAN4
Organisms: Homo sapiens
Libraries: SMILE-seq 1.0 1
1 Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Uniprot: Q8NAM6
Notes: TF family: SCAN+C2H2
Length: 432
Pfam Domains:    40-129 SCAN domain
  301-323 Zinc-finger double domain
  312-334 C2H2-type zinc finger
  312-334 Zinc finger, C2H2 type
  326-349 Zinc-finger double domain
  340-362 Zinc finger, C2H2 type
  340-362 C2H2-type zinc finger
  354-379 Zinc-finger double domain
  368-390 Zinc finger, C2H2 type
  368-390 C2H2-type zinc finger
  382-405 Zinc-finger double domain
  396-418 Zinc finger, C2H2 type
  396-418 C2H2-type zinc finger
Sequence: 
(in bold interface residues)		   1 MALDLRTIFQCEPSENNLGSENSAFQQSQGPAVQREEGISEFSRMVLNSFQDSNNSYARQ   60
  61 ELQRLYRIFHSWLQPEKHSKDEIISLLVLEQFMIGGHCNDKASVKEKWKSSGKNLERFIE  120
 121 DLTDDSINPPALVHVHMQGQEALFSEDMPLRDVIVHLTKQVNAQTTREANMGTPSQTSQD  180
 181 TSLETGQGYEDEQDGWNSSSKTTRVNENITNQGNQIVSLIIIQEENGPRPEEGGVSSDNP  240
 241 YNSKRAELVTARSQEGSINGITFQGVPMVMGAGCISQPEQSSPESALTHQSNEGNSTCEV  300
 301 HQKGSHGVQKSYKCEECPKVFKYLCHLLAHQRRHRNERPFVCPECQKGFFQISDLRVHQI  360
 361 IHTGKKPFTCSMCKKSFSHKTNLRSHERIHTGEKPYTCPFCKTSYRQSSTYHRHMRTHEK  420
 421 ITLPSVPSTPEA
Interface Residues: 312, 322, 323, 324, 325, 326, 328, 329, 331, 332, 335, 350, 351, 352, 353, 354, 356, 357, 360, 378, 379, 380, 381, 382, 383, 384, 385, 386, 388, 389, 393, 406, 407, 408, 409, 410, 411, 412, 413, 414
3D-footprint Homologues: 2kmk_A, 1tf3_A, 5v3j_F, 7w1m_H, 2gli_A, 8ssu_A, 5kkq_D, 5ei9_F, 2drp_D, 8ssq_A, 6e94_A, 7ysf_A, 2jpa_A, 1ubd_C, 8cuc_F, 7y3l_A, 7n5w_A, 6jnm_A, 5yel_A, 4x9j_A, 1g2f_F, 8gn3_A, 5kl3_A, 6ml4_A, 1f2i_J, 6blw_A, 5k5l_F, 8h9h_G, 2lt7_A, 1tf6_A, 7y3m_I, 6a57_A, 3uk3_C, 6u9q_A, 2wbs_A, 5yj3_D, 1llm_D, 7txc_E, 5k5i_A, 4m9v_C, 1yuj_A
Binding Motifs: ZSCAN4 TkymAGyRTGTGy
			
Publications: Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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