Transcription Factor

						

			
Accessions: 6lty_A (3D-footprint 20231221), 6lty_B (3D-footprint 20231221)

			
Names: HIGA3_MYCTU, Putative antitoxin HigA3
Organisms: Mycobacterium tuberculosis, strain ATCC 25618 / H37Rv
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: O53333
Length: 78
Pfam Domains:      2-56 Helix-turn-helix domain
     2-63 Helix-turn-helix domain
     6-60 Helix-turn-helix
Sequence: 
(in bold interface residues)		   1 VLAHRLAEIRKALGHARQADVAALMGVSQARVSKLESGDLSHTELGTLQAYVAALGGHLR   60
  61 IVAEFGENTVELTALEHH
Interface Residues: 28, 29, 30, 31, 33, 34, 39
3D-footprint Homologues: 6lty_B, 3hxo_A
Binding Motifs: 6lty_AB CngAGnnnnACna
6lty_B cygAG
Binding Sites: 6lty_C
6lty_D
			
Publications: Park JY, Kim HJ, Pathak C, Yoon HJ, Kim DH, Park SJ, Lee BJ. Induced DNA bending by unique dimerization of HigA antitoxin. IUCrJ : (2020). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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